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Arch Pediatr. 2021 Aug;28(6):488-490. doi: 10.1016/j.arcped.2021.04.012. Epub 2021 Jul 08.

A rare association between group A Streptococcus purpura fulminans and diffuse alveolar hemorrhage in a young girl: A case report.

Archives de pediatrie : organe officiel de la Societe francaise de pediatrie

E Cousin, T Gaillot, B Ozanne, A Ryckewaert, S Dessard, O Tirel, J-L Fausser

Affiliations

  1. Pediatric Intensive Care Unit, Rennes University Hospital, 35200 Rennes, France. Electronic address: [email protected].
  2. Pediatric Intensive Care Unit, Rennes University Hospital, 35200 Rennes, France.
  3. Pediatric Department, Rennes University Hospital, 35200 Rennes, France.

PMID: 34246502 DOI: 10.1016/j.arcped.2021.04.012

Abstract

We report the case of a 7-year-old girl with septic shock and coagulopathy associated with purpura fulminans (PF) and diffuse alveolar hemorrhage (DAH) due to group A Streptococcus (GAS) infection identified with 16S ribosomal RNA analysis performed on the skin biopsy. GAS infection with PF associated with DAH is rare in healthy young children but pediatricians should be aware of this condition because of the poor prognosis. The initial treatment for circulatory failure and severe disseminated intravascular coagulation as well as the prompt initiation of antibiotic treatment may be crucial for the outcomes of S. pyogenes PF.

Copyright © 2021 French Society of Pediatrics. Published by Elsevier Masson SAS. All rights reserved.

Keywords: Diffuse alveolar hemorrhage; Group A Streptococcus; Purpura fulminans

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