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Kennon AM, Stewart JA. RAGE Differentially Altered . Front Physiol. 2021;12:676727doi: 10.3389/fphys.2021.676727.
Kennon, A. M., & Stewart, J. A. (2021). RAGE Differentially Altered . Frontiers in physiology, 12676727. https://doi.org/10.3389/fphys.2021.676727
Kennon, Amber M, and Stewart, James A. "RAGE Differentially Altered ." Frontiers in physiology vol. 12 (2021): 676727. doi: https://doi.org/10.3389/fphys.2021.676727
Kennon AM, Stewart JA. RAGE Differentially Altered . Front Physiol. 2021 Jun 07;12:676727. doi: 10.3389/fphys.2021.676727. eCollection 2021. PMID: 34163373; PMCID: PMC8215351.
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Front Physiol. 2021 Jun 07;12:676727. doi: 10.3389/fphys.2021.676727. eCollection 2021.

RAGE Differentially Altered .

Frontiers in physiology

Amber M Kennon, James A Stewart

Affiliations

  1. Department of BioMolecular Sciences, School of Pharmacy, University of Mississippi, Mississippi, MS, United States.

PMID: 34163373 PMCID: PMC8215351 DOI: 10.3389/fphys.2021.676727

Abstract

The Advanced Glycation End-Products (AGE)/Receptor for AGEs (RAGE) signaling pathway exacerbates diabetes-mediated vascular calcification (VC) in vascular smooth muscle cells (VSMCs). Other cell types are involved in VC, such as adventitial fibroblasts (AFBs). We hope to elucidate some of the mechanisms responsible for differential signaling in diabetes-mediated VC with this work. This work utilizes RAGE knockout animals and

Copyright © 2021 Kennon and Stewart.

Keywords: AGEs; RAGE; adventitial fibroblasts; diabetes mellitus; vascular calcification; vascular smooth muscle cells

Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

References

  1. Genesis. 2001 May;30(1):36-44 - PubMed
  2. J Diabetes Complications. 2002 Jan-Feb;16(1):65-8 - PubMed
  3. Nature. 1996 Feb 15;379(6566):632-5 - PubMed
  4. Biochem Biophys Res Commun. 1999 May 19;258(3):722-6 - PubMed
  5. Circ Res. 2001 Dec 7;89(12):1147-54 - PubMed
  6. Metabolism. 2011 Sep;60(9):1334-9 - PubMed
  7. Arterioscler Thromb Vasc Biol. 2017 Feb;37(2):191-204 - PubMed
  8. Nat Med. 2009 Nov;15(11):1298-306 - PubMed
  9. Mol Neurobiol. 2018 Feb;55(2):1463-1476 - PubMed
  10. Biol Pharm Bull. 2011;34(5):618-23 - PubMed
  11. Nat Rev Endocrinol. 2018 Feb;14(2):88-98 - PubMed
  12. Circ Res. 2011 Sep 2;109(6):697-711 - PubMed
  13. Circ Res. 2015 Aug 28;117(6):513-24 - PubMed
  14. J Int Med Res. 2009 May-Jun;37(3):847-54 - PubMed
  15. J Cell Biol. 1971 Jul;50(1):172-86 - PubMed
  16. Trends Mol Med. 2009 Aug;15(8):369-79 - PubMed
  17. J Pathol. 2005 Apr;205(5):641-50 - PubMed
  18. J Leukoc Biol. 2010 Nov;88(5):1051-9 - PubMed
  19. Mol Immunol. 2013 Dec;56(4):739-44 - PubMed
  20. Cell Mol Life Sci. 2014 Jun;71(12):2271-88 - PubMed
  21. Curr Pharm Des. 2003;9(32):2677-85 - PubMed
  22. Am J Physiol Renal Physiol. 2014 Oct 15;307(8):F891-900 - PubMed
  23. BMC Cardiovasc Disord. 2013 Mar 05;13:13 - PubMed
  24. J Biol Chem. 2000 Jun 30;275(26):20197-203 - PubMed
  25. Metabolism. 2000 Jan;49(1):22-31 - PubMed
  26. Arterioscler Thromb Vasc Biol. 2017 Sep;37(9):1598-1607 - PubMed
  27. Mediators Inflamm. 2020 Aug 7;2020:6850187 - PubMed
  28. Am J Pathol. 2007 Jul;171(1):116-23 - PubMed
  29. J Cardiovasc Pharmacol. 2011 Apr;57(4):376-9 - PubMed
  30. Horm Cancer. 2018 Oct;9(5):295-325 - PubMed
  31. Am J Kidney Dis. 2001 Oct;38(4 Suppl 1):S34-7 - PubMed
  32. J Allergy Clin Immunol. 2019 Sep;144(3):796-808.e12 - PubMed
  33. Biomed Res Int. 2018 Aug 26;2018:7675286 - PubMed
  34. J Clin Invest. 1994 May;93(5):2007-13 - PubMed
  35. Cell. 1996 Feb 9;84(3):491-5 - PubMed
  36. J Am Coll Cardiol. 2008 Sep 2;52(10):843-50 - PubMed
  37. Porto Biomed J. 2017 Nov-Dec;2(6):301-305 - PubMed
  38. PLoS One. 2015 Aug 06;10(8):e0128881 - PubMed
  39. Endocrinology. 2012 Aug;153(8):3897-910 - PubMed
  40. J Am Soc Nephrol. 2004 Dec;15(12):2959-64 - PubMed
  41. Horm Metab Res. 2013 Apr;45(4):267-72 - PubMed
  42. Cardiovasc Res. 2005 May 1;66(2):324-33 - PubMed
  43. Nucleic Acids Res. 1995 Dec 25;23(24):5080-1 - PubMed
  44. J Am Heart Assoc. 2020 Dec;9(23):e017094 - PubMed
  45. J Cell Biochem. 2010 Jul 1;110(4):935-47 - PubMed
  46. Arterioscler Thromb Vasc Biol. 2013 Nov;33(11):2625-32 - PubMed
  47. Arterioscler Thromb Vasc Biol. 2019 Apr;39(4):613-622 - PubMed
  48. Cell Stem Cell. 2017 Feb 2;20(2):218-232.e5 - PubMed
  49. Immunobiology. 2020 Mar;225(2):151879 - PubMed
  50. Circ Res. 2005 Apr 15;96(7):717-22 - PubMed
  51. Arterioscler Thromb Vasc Biol. 2020 May;40(5):1078-1093 - PubMed
  52. J Cell Commun Signal. 2013 Mar;7(1):19-23 - PubMed
  53. Cardiovasc Res. 1998 Mar;37(3):586-600 - PubMed
  54. Redox Biol. 2016 Oct;9:244-253 - PubMed
  55. Diabet Med. 2019 Jun;36(6):718-725 - PubMed
  56. Circ Res. 2011 Feb 18;108(4):446-57 - PubMed
  57. J Biomed Sci. 2017 Sep 7;24(1):70 - PubMed
  58. Cell Res. 2005 Jan;15(1):11-8 - PubMed
  59. Cancers (Basel). 2017 May 17;9(5): - PubMed
  60. J Clin Invest. 2004 Jun;113(11):1641-50 - PubMed
  61. Arterioscler Thromb Vasc Biol. 2007 Nov;27(11):2302-9 - PubMed
  62. Circ Res. 2010 Oct 29;107(9):1058-70 - PubMed
  63. World J Diabetes. 2015 May 15;6(4):598-612 - PubMed
  64. Cardiovasc Diabetol. 2013 Oct 05;12:142 - PubMed
  65. J Biomark. 2013;2013:378790 - PubMed
  66. Mol Vis. 2011 Feb 17;17:508-18 - PubMed
  67. J Vasc Res. 2009;46(6):572-80 - PubMed
  68. Circulation. 2008 Jun 3;117(22):2938-48 - PubMed
  69. J Clin Invest. 2005 May;115(5):1210-20 - PubMed
  70. Thromb Haemost. 2010 Sep;104(3):464-70 - PubMed
  71. J Biol Chem. 2017 Sep 29;292(39):16161-16173 - PubMed
  72. Mol Med Rep. 2012 Jul;6(1):179-84 - PubMed
  73. Life Sci. 2020 Jun 1;250:117569 - PubMed
  74. Free Radic Biol Med. 2002 Aug 1;33(3):337-49 - PubMed
  75. Int J Mol Med. 2012 Apr;29(4):613-8 - PubMed
  76. PLoS One. 2018 Aug 17;13(8):e0202323 - PubMed
  77. PLoS One. 2011;6(8):e23132 - PubMed
  78. Cardiovasc Res. 2007 Sep 1;75(4):702-9 - PubMed
  79. Biochim Biophys Acta. 2012 May;1820(5):663-71 - PubMed
  80. Exp Neurol. 2007 Dec;208(2):216-27 - PubMed
  81. Diabetes. 2001 Jun;50(6):1495-504 - PubMed
  82. Science. 1996 Feb 16;271(5251):994-6 - PubMed
  83. J Biol Chem. 2007 Aug 10;282(32):23427-36 - PubMed
  84. Circulation. 2002 Aug 13;106(7):854-9 - PubMed
  85. Am J Med. 2009 Apr;122(4):380-6 - PubMed
  86. Diabetologia. 2001 Feb;44(2):129-46 - PubMed
  87. Arterioscler Thromb Vasc Biol. 2017 Feb;37(2):205-217 - PubMed
  88. Diabetes. 2010 Jan;59(1):249-55 - PubMed
  89. Exp Ther Med. 2019 Jan;17(1):863-868 - PubMed
  90. J Vasc Surg. 2007 Jun;45 Suppl A:A25-32 - PubMed
  91. J Biol Chem. 2008 May 30;283(22):15319-27 - PubMed
  92. J Alzheimers Dis. 2009;16(4):845-58 - PubMed
  93. J Atheroscler Thromb. 2011;18(8):670-83 - PubMed
  94. Anat Rec (Hoboken). 2018 Jul;301(7):1216-1223 - PubMed
  95. PLoS One. 2015 Jul 06;10(7):e0132506 - PubMed
  96. Cardiovasc Res. 2018 Mar 15;114(4):590-600 - PubMed
  97. Cell Death Dis. 2020 Jan 10;11(1):22 - PubMed
  98. Diabetes. 2005 Jun;54(6):1615-25 - PubMed
  99. J Inflamm Res. 2018 Oct 30;11:407-419 - PubMed
  100. J Biol Chem. 2001 Jul 27;276(30):28261-7 - PubMed
  101. Circulation. 2000 Jun 27;101(25):2949-55 - PubMed
  102. Int J Physiol Pathophysiol Pharmacol. 2019 Jun 15;11(3):45-63 - PubMed

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