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Dekan Z, Kremsmayr T, Keov P, et al. Nature-inspired dimerization as a strategy to modulate neuropeptide pharmacology exemplified with vasopressin and oxytocin. Chem Sci. 2021;12(11):4057-4062doi: 10.1039/d0sc05501h.
Dekan, Z., Kremsmayr, T., Keov, P., Godin, M., Teakle, N., Dürrauer, L., Xiang, H., Gharib, D., Bergmayr, C., Hellinger, R., Gay, M., Vilaseca, M., Kurzbach, D., Albericio, F., Alewood, P. F., Gruber, C. W., & Muttenthaler, M. (2021). Nature-inspired dimerization as a strategy to modulate neuropeptide pharmacology exemplified with vasopressin and oxytocin. Chemical science, 12(11), 4057-4062. https://doi.org/10.1039/d0sc05501h
Dekan, Zoltan, et al. "Nature-inspired dimerization as a strategy to modulate neuropeptide pharmacology exemplified with vasopressin and oxytocin." Chemical science vol. 12,11 (2021): 4057-4062. doi: https://doi.org/10.1039/d0sc05501h
Dekan Z, Kremsmayr T, Keov P, Godin M, Teakle N, Dürrauer L, Xiang H, Gharib D, Bergmayr C, Hellinger R, Gay M, Vilaseca M, Kurzbach D, Albericio F, Alewood PF, Gruber CW, Muttenthaler M. Nature-inspired dimerization as a strategy to modulate neuropeptide pharmacology exemplified with vasopressin and oxytocin. Chem Sci. 2021 Feb 04;12(11):4057-4062. doi: 10.1039/d0sc05501h. PMID: 34163676; PMCID: PMC8179488.
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Chem Sci. 2021 Feb 04;12(11):4057-4062. doi: 10.1039/d0sc05501h.

Nature-inspired dimerization as a strategy to modulate neuropeptide pharmacology exemplified with vasopressin and oxytocin.

Chemical science

Zoltan Dekan, Thomas Kremsmayr, Peter Keov, Mathilde Godin, Ngari Teakle, Leopold Dürrauer, Huang Xiang, Dalia Gharib, Christian Bergmayr, Roland Hellinger, Marina Gay, Marta Vilaseca, Dennis Kurzbach, Fernando Albericio, Paul F Alewood, Christian W Gruber, Markus Muttenthaler

Affiliations

  1. Institute for Molecular Bioscience, The University of Queensland Brisbane 4072 Australia [email protected].
  2. Institute of Biological Chemistry, University of Vienna Währingerstraße 38 1090 Vienna Austria [email protected].
  3. Faculty of Medicine, School of Biomedical Sciences, The University of Queensland Brisbane 4072 Australia.
  4. Center for Physiology and Pharmacology, Medical University of Vienna Schwarzspanierstraße 17 1090 Vienna Austria [email protected].
  5. Institute for Research in Biomedicine Barcelona C/ Baldiri Reixac 10 08028 Barcelona Spain.
  6. Department of Organic Chemistry, University of Barcelona Barcelona Science Park, Baldiri Reixac 10 08028 Barcelona Spain.

PMID: 34163676 PMCID: PMC8179488 DOI: 10.1039/d0sc05501h

Abstract

Vasopressin (VP) and oxytocin (OT) are cyclic neuropeptides that regulate fundamental physiological functions

This journal is © The Royal Society of Chemistry.

Conflict of interest statement

There are no conflicts to declare.

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