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Eur Cardiol. 2021 Jun 18;16:e26. doi: 10.15420/ecr.2020.45. eCollection 2021 Feb.

2020 Asian Pacific Society of Cardiology Consensus Recommendations on Antithrombotic Management for High-risk Chronic Coronary Syndrome.

European cardiology

Jack Wei Chieh Tan, Derek P Chew, David Brieger, John Eikelboom, Gilles Montalescot, Junya Ako, Byeong-Keuk Kim, David Kl Quek, Sarah J Aitken, Clara K Chow, Sok Chour, Hung Fat Tse, Upendra Kaul, Isman Firdaus, Takashi Kubo, Boon Wah Liew, Tze Tec Chong, Kenny Yk Sin, Hung-I Yeh, Wacin Buddhari, Narathip Chunhamaneewat, Faisal Hasan, Keith Aa Fox, Quang Ngoc Nguyen, Sidney Th Lo

Affiliations

  1. National Heart Centre Singapore.
  2. Sengkang General Hospital Singapore.
  3. College of Medicine and Public Health, Flinders University Adelaide, Australia.
  4. Concord Repatriation General Hospital, University of Sydney Sydney, Australia.
  5. McMaster University Ontario, Canada.
  6. Sorbonne University Paris, France.
  7. ACTION Study Group France.
  8. Pitié-Salpêtrière University Hospital (AP-HP) Paris, France.
  9. Kitasato University and Hospital Kanagawa, Japan.
  10. Yonsei University College of Medicine South Korea.
  11. Pantai Hospital Kuala Lumpur Kuala Lumpur, Malaysia.
  12. University of Sydney Sydney, Australia.
  13. Westmead Applied Research Centre, University of Sydney Sydney, Australia.
  14. Westmead Hospital Sydney, Australia.
  15. Calmette Hospital Phnom Penh, Cambodia.
  16. Queen Mary Hospital, University of Hong Kong Hong Kong, China.
  17. Batra Hospital and Medical Research Center New Delhi, India.
  18. Faculty of Medicine, University of Indonesia Jakarta, Indonesia.
  19. Wakayama Medical University Wakayama, Japan.
  20. Changi General Hospital Singapore.
  21. Singapore General Hospital Singapore.
  22. MacKay Memorial Hospital, MacKay Medical College Taipei, Taiwan.
  23. King Chulalongkorn Memorial Hospital Bangkok, Thailand.
  24. Siriraj Hospital, Mahidol University Bangkok, Thailand.
  25. Heart & Vascular Institute, Cleveland Clinic Abu Dhabi Abu Dhabi, United Arab Emirates.
  26. University of Edinburgh Edinburgh, UK.
  27. Hanoi Medical University, Vietnam National Heart Institute Hanoi, Vietnam.
  28. Liverpool Hospital Sydney, Australia.

PMID: 34249148 PMCID: PMC8251506 DOI: 10.15420/ecr.2020.45

Abstract

The unique characteristics of patients with chronic coronary syndrome (CCS) in the Asia-Pacific region, heterogeneous approaches because of differences in accesses and resources and low number of patients from the Asia-Pacific region in pivotal studies, mean that international guidelines cannot be routinely applied to these populations. The Asian Pacific Society of Cardiology developed these consensus recommendations to summarise current evidence on the management of CCS and provide recommendations to assist clinicians treat patients from the region. The consensus recommendations were developed by an expert consensus panel who reviewed and appraised the available literature, with focus on data from patients in Asia-Pacific. Consensus statements were developed then put to an online vote. The resulting recommendations provide guidance on the assessment and management of bleeding and ischaemic risks in Asian CCS patients. Furthermore, the selection of long-term antithrombotic therapy is discussed, including the role of single antiplatelet therapy, dual antiplatelet therapy and dual pathway inhibition therapy.

Copyright © 2021, Radcliffe Cardiology.

Keywords: Asia-Pacific; anticoagulant; antiplatelet; bleeding; chronic coronary syndrome; consensus; ischaemia

Conflict of interest statement

Disclosure: This work was funded through the Asian Pacific Society of Cardiology with unrestricted educational grants from Abbott Vascular, Amgen, AstraZeneca, Bayer and Roche Diagnostics. JWCT report

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