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Case Rep Endocrinol. 2021 Jun 12;2021:9925707. doi: 10.1155/2021/9925707. eCollection 2021.

Bacteremia in a Newborn with Hypocalcemic Seizures and Vitamin D Deficiency.

Case reports in endocrinology

Rebecca L Moore, Matthew L Lorenz, Meghan E Fredette, Lisa Swartz Topor

Affiliations

  1. Department of Pediatrics, Brown University, Providence, RI, USA.
  2. Department of Internal Medicine, Rhode Island Hospital, Providence, RI, USA.
  3. Department of Internal Medicine, Brown University, Providence, RI, USA.
  4. Division of Pediatric Endocrinology, Hasbro Children's Hospital, Providence, RI, USA.

PMID: 34194851 PMCID: PMC8214477 DOI: 10.1155/2021/9925707

Abstract

Infants with neonatal hypocalcemia often present with seizures, and neonatal hypocalcemia can be due to parathyroid (PTH) insufficiency or resistance. Causes of hypocalcemia with PTH elevation include increased phosphate load, vitamin D deficiency (VDD) or defects in metabolism, renal dysfunction, hypomagnesemia, genetic mutations resulting in end-organ resistance to PTH, or critical illness. Hypocalcemia has also been shown to be associated with Gram-negative bacteremia and sepsis in adults. We present the case of a full-term, formula-fed newborn presenting with late-onset hypocalcemic seizures and VDD in the setting of

Copyright © 2021 Rebecca L. Moore et al.

Conflict of interest statement

The authors declare that they have no conflicts of interest.

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