Display options
Cite
de Paula Silva L, de Moraes Rego FG, Picheth G, et al. Prospection of plasma proteins as biomarkers for diabetes mellitus monitoring. J Diabetes Metab Disord. 2021;20(1):611-620doi: 10.1007/s40200-021-00788-1.
de Paula Silva, L., de Moraes Rego, F. G., Picheth, G., Müller-Santos, M., & Alberton, D. (2021). Prospection of plasma proteins as biomarkers for diabetes mellitus monitoring. Journal of diabetes and metabolic disorders, 20(1), 611-620. https://doi.org/10.1007/s40200-021-00788-1
de Paula Silva, Liliane, et al. "Prospection of plasma proteins as biomarkers for diabetes mellitus monitoring." Journal of diabetes and metabolic disorders vol. 20,1 (2021): 611-620. doi: https://doi.org/10.1007/s40200-021-00788-1
de Paula Silva L, de Moraes Rego FG, Picheth G, Müller-Santos M, Alberton D. Prospection of plasma proteins as biomarkers for diabetes mellitus monitoring. J Diabetes Metab Disord. 2021 Mar 29;20(1):611-620. doi: 10.1007/s40200-021-00788-1. eCollection 2021 Jun. PMID: 34222081; PMCID: PMC8212233.
Copy Download .nbib Format: NLM
Share it on

J Diabetes Metab Disord. 2021 Mar 29;20(1):611-620. doi: 10.1007/s40200-021-00788-1. eCollection 2021 Jun.

Prospection of plasma proteins as biomarkers for diabetes mellitus monitoring.

Journal of diabetes and metabolic disorders

Liliane de Paula Silva, Fabiane Gomes de Moraes Rego, Geraldo Picheth, Marcelo Müller-Santos, Dayane Alberton

Affiliations

  1. Graduate Program in Pharmaceutical Science, Department of Clinical Analysis, Federal University of Paraná, Rua Prefeito Lothário Meissner, 632, Curitiba, PR 80210-170 Brazil.
  2. Graduate Program in Sciences - Biochemistry, Department of Biochemistry and Molecular Biology, Federal University of Paraná, Curitiba, PR Brazil.

PMID: 34222081 PMCID: PMC8212233 DOI: 10.1007/s40200-021-00788-1

Abstract

PURPOSE: This prospective study aimed to detect and identify plasma proteins differentially expressed between groups of Brazilian diagnosed with type 1 (T1DM), type 2 (T2DM) diabetes with good and poor glycemic control and the non-diabetic group denominated control group (CG).

METHODS: Patients with T1DM and T2DM were subdivided according to their glycated haemoglobin (HbA

RESULTS: Alpha 2 - Macroglobulin (AMG) was 1.3-fold more abundant in T1DM with HbA

CONCLUSION: In summary, three positive acute-phase proteins, AMG, Cp and Hp were more abundant in diabetic individuals regardless of the diabetes type. The highest Hp abundance in both types of DM with HbA

© Springer Nature Switzerland AG 2021.

Keywords: Apolipoprotein A-I; Ceruloplasmin; Glycemic control; Haptoglobins; Type 1 diabetes; Type 2 diabetes

Conflict of interest statement

Conflict of interestOn behalf of all authors, the corresponding author states that there is no conflict of interest.

References

  1. Free Radic Res. 2002 May;36(5):521-9 - PubMed
  2. Diabetes Care. 2020 Jan;43(Suppl 1):S14-S31 - PubMed
  3. Biofactors. 2017 May 6;43(3):424-433 - PubMed
  4. Dis Markers. 2015;2015:128653 - PubMed
  5. Cardiovasc Diabetol. 2017 Jul 6;16(1):85 - PubMed
  6. Metallomics. 2016 Sep 1;8(9):887-905 - PubMed
  7. Clin Chem. 1996 Oct;42(10):1589-600 - PubMed
  8. J Pharm Biomed Anal. 2010 Apr 6;51(5):1103-7 - PubMed
  9. Clin Diabetes. 2016 Jul;34(3):148-57 - PubMed
  10. Am J Clin Pathol. 2004 Jun;121 Suppl:S97-104 - PubMed
  11. Diabetes. 2010 Oct;59(10):2358-9 - PubMed
  12. Endocrinol Diabetes Nutr (Engl Ed). 2019 Feb;66(2):99-107 - PubMed
  13. Sci Rep. 2019 Sep 10;9(1):12927 - PubMed
  14. Clin Exp Med. 2010 Sep;10(3):185-92 - PubMed
  15. J Am Coll Cardiol. 2015 Oct 20;66(16):1791-1799 - PubMed
  16. J Diabetes Res. 2018 May 20;2018:6125420 - PubMed
  17. Diabetes. 2010 Oct;59(10):2366-74 - PubMed
  18. Clin Chem. 2002 Sep;48(9):1377-82 - PubMed
  19. Indian J Clin Biochem. 2016 Jul;31(3):253-9 - PubMed
  20. J Diabetes Investig. 2016 Mar;7(2):190-6 - PubMed
  21. Clin Transl Med. 2014 Mar 29;3(1):7 - PubMed
  22. J Cell Physiol. 2013 Aug;228(8):1665-75 - PubMed
  23. Electrophoresis. 2004 May;25(9):1327-33 - PubMed
  24. Atherosclerosis. 2013 May;228(1):270-6 - PubMed
  25. Circ Res. 2005 Mar 4;96(4):435-41 - PubMed
  26. Arch Biochem Biophys. 2013 Jan 15;529(2):146-56 - PubMed
  27. Cholesterol. 2012;2012:490381 - PubMed
  28. Nucleic Acids Res. 1991 Oct 11;19(19):5444 - PubMed
  29. Diabetes Metab J. 2015 Jun;39(3):230-9 - PubMed
  30. J Am Coll Cardiol. 2002 Dec 4;40(11):1984-90 - PubMed
  31. J Clin Lipidol. 2017 Mar - Apr;11(2):362-368 - PubMed
  32. Atherosclerosis. 2006 May;186(1):173-6 - PubMed
  33. Metabolism. 1995 Aug;44(8):996-9 - PubMed
  34. Circ Res. 2003 Jun 13;92(11):1193-200 - PubMed
  35. Diabetologia. 2019 Nov;62(11):1998-2006 - PubMed
  36. Diabetes Care. 1998 Sep;21(9):1525-8 - PubMed

Publication Types