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Razanamahery J, Humbert S, Emile JF, et al. Immune Thrombocytopenia Revealing Enriched IgG-4 Peri-Renal Rosai-Dorfman Disease Successfully Treated with Rituximab: A Case Report and Literature Review. Front Med (Lausanne). 2021;8:678456doi: 10.3389/fmed.2021.678456.
Razanamahery, J., Humbert, S., Emile, J. F., Cohen-Aubart, F., Fontan, J., Maksud, P., Audia, S., & Haroche, J. (2021). Immune Thrombocytopenia Revealing Enriched IgG-4 Peri-Renal Rosai-Dorfman Disease Successfully Treated with Rituximab: A Case Report and Literature Review. Frontiers in medicine, 8678456. https://doi.org/10.3389/fmed.2021.678456
Razanamahery, Jerome, et al. "Immune Thrombocytopenia Revealing Enriched IgG-4 Peri-Renal Rosai-Dorfman Disease Successfully Treated with Rituximab: A Case Report and Literature Review." Frontiers in medicine vol. 8 (2021): 678456. doi: https://doi.org/10.3389/fmed.2021.678456
Razanamahery J, Humbert S, Emile JF, Cohen-Aubart F, Fontan J, Maksud P, Audia S, Haroche J. Immune Thrombocytopenia Revealing Enriched IgG-4 Peri-Renal Rosai-Dorfman Disease Successfully Treated with Rituximab: A Case Report and Literature Review. Front Med (Lausanne). 2021 Jun 16;8:678456. doi: 10.3389/fmed.2021.678456. eCollection 2021. PMID: 34222286; PMCID: PMC8244783.
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Front Med (Lausanne). 2021 Jun 16;8:678456. doi: 10.3389/fmed.2021.678456. eCollection 2021.

Immune Thrombocytopenia Revealing Enriched IgG-4 Peri-Renal Rosai-Dorfman Disease Successfully Treated with Rituximab: A Case Report and Literature Review.

Frontiers in medicine

Jerome Razanamahery, Sebastien Humbert, Jean-Francois Emile, Fleur Cohen-Aubart, Jean Fontan, Philippe Maksud, Sylvain Audia, Julien Haroche

Affiliations

  1. Internal Medicine Department and Clinical Immunology, Dijon University Hospital, Dijon, France.
  2. Internal Medicine Department, Besancon University Hospital, Besançon, France.
  3. Department of Pathology, Ambroise-Paré Hospital, Assistance-Publique Hopitaux de Paris, Paris, France.
  4. Sorbonne Université, Assistance Publique Hôpitaux de Paris, Pitié-Salpêtrière Hospital, Internal Medicine Department 2, National Reference Center for Histiocytosis, Paris, France.
  5. Department of Haematology, Besancon University Hospital, Besançon, France.
  6. Department of Nuclear Medicine, Pitié-Salpêtrière Hospital, Paris, France.

PMID: 34222286 PMCID: PMC8244783 DOI: 10.3389/fmed.2021.678456

Abstract

Immune thrombocytopenia (ITP) is a rare autoimmune-mediated condition characterized by isolated thrombocytopenia (<100 G/L) after exclusion of other causes. Mostly primary, it is associated with hematological malignancy, autoimmune disorders, or infection in 20% of patients. It is exceptionally described in patients with histiocytosis, mostly in children (seven patients in literature). We report a case of a 69-year-old man with ITP leading to the diagnosis of histiocytosis. At ITP's diagnosis, the patient had elevated gamma-globulins leading to computed tomography showing bilateral peri-renal infiltration. The biopsy showed enriched IgG-4 peri-renal Rosai Dorfman disease with

Copyright © 2021 Razanamahery, Humbert, Emile, Cohen-Aubart, Fontan, Maksud, Audia and Haroche.

Keywords: Erdheim Chester disease; Rosai Dorfman disease; histiocytosis; immune thrombocytopenia; rituximab

Conflict of interest statement

FC-A and JH are investigators (FC-A being the PI) of an academic study on the efficacy of cobimetinib for treating histiocytoses. The remaining authors declare that the research was conducted in the a

References

  1. Adv Immunol. 2013;120:127-61 - PubMed
  2. Nature. 2005 Aug 4;436(7051):720-4 - PubMed
  3. Blood. 2020 Apr 16;135(16):1311-1318 - PubMed
  4. Am J Case Rep. 2019 May 31;20:770-772 - PubMed
  5. J Pediatr Hematol Oncol. 2007 May;29(5):348-50 - PubMed
  6. Am J Surg Pathol. 2006 Sep;30(9):1189-92 - PubMed
  7. Blood Adv. 2019 Nov 26;3(22):3780-3817 - PubMed
  8. Haematologica. 2020 Feb 27;106(1):250-254 - PubMed
  9. Am J Hematol. 2019 Dec;94(12):1314-1324 - PubMed
  10. Blood. 2020 Apr 16;135(16):1319-1331 - PubMed
  11. J Neurosurg. 2012 Sep;117(3):486-9 - PubMed
  12. Rev Bras Ginecol Obstet. 2018 Dec;40(12):803-807 - PubMed
  13. Abdom Imaging. 2002 Mar-Apr;27(2):214-6 - PubMed
  14. J Pediatr Hematol Oncol. 2019 Nov;41(8):620-623 - PubMed
  15. Blood. 2017 Jul 13;130(2):176-180 - PubMed
  16. Haematologica. 2020 Jan 31;105(2):348-357 - PubMed
  17. Blood. 2018 Jun 28;131(26):2877-2890 - PubMed
  18. Blood. 2014 Oct 30;124(18):2858-66 - PubMed
  19. Nature. 2019 Mar;567(7749):521-524 - PubMed
  20. Haematologica. 2020 Jan;105(1):e5-e8 - PubMed
  21. Blood. 2021 Jan 28;137(4):485-492 - PubMed
  22. Blood. 2014 Nov 20;124(22):3228-36 - PubMed
  23. Blood. 2017 May 25;129(21):2829-2835 - PubMed
  24. Blood. 2017 Jul 13;130(2):167-175 - PubMed
  25. Case Rep Oncol. 2020 Apr 14;13(1):408-413 - PubMed
  26. Haematologica. 2019 Nov;104(11):e502-e505 - PubMed
  27. J Exp Med. 2018 Jan 2;215(1):319-336 - PubMed
  28. Lancet Neurol. 2017 Dec;16(12):953-954 - PubMed

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