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Goto Y, Funada A, Maeda T, et al. Time boundaries of the three-phase time-sensitive model for ventricular fibrillation cardiac arrest. Resusc Plus. 2021;6:100095doi: 10.1016/j.resplu.2021.100095.
Goto, Y., Funada, A., Maeda, T., & Goto, Y. (2021). Time boundaries of the three-phase time-sensitive model for ventricular fibrillation cardiac arrest. Resuscitation plus, 6100095. https://doi.org/10.1016/j.resplu.2021.100095
Goto, Yoshikazu, et al. "Time boundaries of the three-phase time-sensitive model for ventricular fibrillation cardiac arrest." Resuscitation plus vol. 6 (2021): 100095. doi: https://doi.org/10.1016/j.resplu.2021.100095
Goto Y, Funada A, Maeda T, Goto Y. Time boundaries of the three-phase time-sensitive model for ventricular fibrillation cardiac arrest. Resusc Plus. 2021 Mar 02;6:100095. doi: 10.1016/j.resplu.2021.100095. eCollection 2021 Jun. PMID: 34223360; PMCID: PMC8244403.
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Resusc Plus. 2021 Mar 02;6:100095. doi: 10.1016/j.resplu.2021.100095. eCollection 2021 Jun.

Time boundaries of the three-phase time-sensitive model for ventricular fibrillation cardiac arrest.

Resuscitation plus

Yoshikazu Goto, Akira Funada, Tetsuo Maeda, Yumiko Goto

Affiliations

  1. Department of Emergency and Critical Care Medicine, Kanazawa University Hospital, Takaramachi 13-1, Kanazawa 920-8640, Japan.
  2. Department of Cardiology, Osaka Saiseikai Senri Hospital, Tsukumodai 1-1-6, Suita 565-0862, Japan.
  3. Department of Cardiology, Yawata Medical Center, Yawata I 12-7, Komatsu 923-8551, Japan.

PMID: 34223360 PMCID: PMC8244403 DOI: 10.1016/j.resplu.2021.100095

Abstract

AIM: Ventricular fibrillation (VF) cardiac arrest may consist of three time-sensitive phases: electrical, circulatory, and metabolic. However, the time boundaries of these phases are unclear. We aimed to determine the time boundaries of the three-phase model for VF cardiac arrest.

METHODS: We reviewed 20,741 out-of-hospital cardiac arrest cases with initial VF and presumed cardiac origin from the All-Japan Utstein-style registry between 2013 and 2017. The study endpoint was 1-month neurologically intact survival. The collapse-to-shock interval was defined as the time from collapse to the first shock delivery by emergency medical service personnel. The patients were divided into the bystander cardiopulmonary resuscitation (CPR,

RESULTS: In the bystander CPR group, the collapse-to-shock times that were associated with increased adjusted 1-month neurologically intact survival, compared with those in the non-bystander CPR group, ranged from 7 min (42.9% [244/4999] vs. 26.0% [119/458], adjusted odds ratio [aOR], 1.95; 95% confidence interval [CI], 1.44-2.63;

CONCLUSIONS: The time boundaries of the three-phase time-sensitive model for VF cardiac arrest may be defined as follows: electrical phase, from collapse to <7 min; circulatory phase, from 7 to 17 min; and metabolic phase, from >17 min onward.

© 2021 The Authors.

Keywords: Cardiac arrest; Cardiopulmonary resuscitation; Epidemiology; Outcomes; Ventricular fibrillation

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