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Parker EL, Silverstein RB, Mysorekar IU. Bacteria make T cell memories in utero. Cell. 2021;184(13):3356-3357doi: 10.1016/j.cell.2021.05.044.
Parker, E. L., Silverstein, R. B., & Mysorekar, I. U. (2021). Bacteria make T cell memories in utero. Cell, 184(13), 3356-3357. https://doi.org/10.1016/j.cell.2021.05.044
Parker, Elaine L, et al. "Bacteria make T cell memories in utero." Cell vol. 184,13 (2021): 3356-3357. doi: https://doi.org/10.1016/j.cell.2021.05.044
Parker EL, Silverstein RB, Mysorekar IU. Bacteria make T cell memories in utero. Cell. 2021 Jun 24;184(13):3356-3357. doi: 10.1016/j.cell.2021.05.044. PMID: 34171317.
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Cell. 2021 Jun 24;184(13):3356-3357. doi: 10.1016/j.cell.2021.05.044.

Bacteria make T cell memories in utero.

Cell

Elaine L Parker, Rachel B Silverstein, Indira U Mysorekar

Affiliations

  1. Department of Obstetrics and Gynecology, Washington University in St. Louis School of Medicine, St. Louis, MO 63110, USA.
  2. Department of Obstetrics and Gynecology, Washington University in St. Louis School of Medicine, St. Louis, MO 63110, USA; Department of Pathology and Immunology, Washington University in St. Louis School of Medicine, St. Louis, MO 63110, USA. Electronic address: [email protected].

PMID: 34171317 DOI: 10.1016/j.cell.2021.05.044

Abstract

Education of the human immune system begins in utero via T cell activation and memory development. However, whether part of the education is provided by exposure to microbes in utero remains controversial and unclear. In this issue of Cell, Mishra et al. provide new evidence that the fetal gut may be colonized by bacteria that prime T cell memories.

Copyright © 2021 Elsevier Inc. All rights reserved.

Conflict of interest statement

Declaration of interests I.U.M. serves on the Scientific Advisory Board of Luca Biologics. No other conflicts of interest exist.

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