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Antibiotics (Basel). 2021 Jun 07;10(6). doi: 10.3390/antibiotics10060680.

Prevalence and Risk Factors for Multidrug-Resistant Organisms Colonization in Long-Term Care Facilities Around the World: A Review.

Antibiotics (Basel, Switzerland)

Ángel Rodríguez-Villodres, Cecilia Martín-Gandul, Germán Peñalva, Ana Belén Guisado-Gil, Juan Carlos Crespo-Rivas, María Eugenia Pachón-Ibáñez, José Antonio Lepe, José Miguel Cisneros

Affiliations

  1. Clinical Unit of Infectious Diseases, Microbiology and Preventive Medicine, Institute of Biomedicine of Seville (IBiS), University of Seville/CSIC/University Hospital Virgen del Rocío, 41013 Seville, Spain.
  2. Department of Pharmacy, University Hospital Virgen del Rocío, 41013 Seville, Spain.

PMID: 34200238 PMCID: PMC8228357 DOI: 10.3390/antibiotics10060680

Abstract

Elderly people confined to chronic care facilities face an increased risk of acquiring infections by multidrug-resistant organisms (MDROs). This review presents the current knowledge of the prevalence and risk factors for colonization by MDROs in long-term care facilities (LTCF), thereby providing a useful reference to establish objectives for implementing successful antimicrobial stewardship programs (ASPs). We searched in PubMed and Scopus for studies examining the prevalence of MDROs and/or risk factors for the acquisition of MDROs in LTCF. One hundred and thirty-four studies published from 1987 to 2020 were included. The prevalence of MDROs in LTCF varies between the different continents, where Asia reported the highest prevalence of extended-spectrum ß-lactamase (ESBL)

Keywords: antimicrobial stewardship; long term care facilities; multidrug-resistant organism; nursing homes; prevalence; risk factors

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