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Antioxid Redox Signal. 2021 Sep 20;35(9):718-733. doi: 10.1089/ars.2021.0102. Epub 2021 Jul 07.

Oxidant Stress and Acetaminophen Hepatotoxicity: Mechanism-Based Drug Development.

Antioxidants & redox signaling

Anup Ramachandran, Hartmut Jaeschke

Affiliations

  1. Department of Pharmacology, Toxicology & Therapeutics, University of Kansas Medical Center, Kansas City, Kansas, USA.

PMID: 34232786 PMCID: PMC8558076 DOI: 10.1089/ars.2021.0102

[No abstract available.]

Keywords: Nrf2; acetaminophen; drug hepatotoxicity; mitochondria; peroxynitrite; therapeutic approaches

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