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J Clin Med. 2021 Jun 19;10(12). doi: 10.3390/jcm10122719.

Impact of Bundle Branch Block on Permanent Pacemaker Implantation after Transcatheter Aortic Valve Implantation: A Meta-Analysis.

Journal of clinical medicine

Justine M Ravaux, Michele Di Mauro, Kevin Vernooy, Silvia Mariani, Daniele Ronco, Jorik Simons, Arnoud W Van't Hof, Leo Veenstra, Suzanne Kats, Jos G Maessen, Roberto Lorusso

Affiliations

  1. Department of Cardio-Thoracic Surgery, Heart and Vascular Centre, Maastricht University Medical Centre (MUMC), 6202 AZ Maastricht, The Netherlands.
  2. Department of Cardiology, Maastricht University Medical Centre (MUMC), 6202 AZ Maastricht, The Netherlands.
  3. Cardiovascular Research Institute Maastricht (CARIM), Maastricht University Medical Center, 6202 AZ Maastricht, The Netherlands.
  4. Department of Cardiology, Radboud University Medical Center (Radboudumc), 6525 GA Nijmegen, The Netherlands.
  5. Department of Medicine and Surgery, Circolo Hospital, University of Insubria, 21100 Varese, VA, Italy.

PMID: 34205478 PMCID: PMC8235153 DOI: 10.3390/jcm10122719

Abstract

Data regarding the impact of infra-Hisian conduction disturbances leading to permanent pacemaker implantation (PPI) after transcatheter aortic valve implantation (TAVI) remain limited. The aim of this study was to determine the impact of right and/or left bundle branch block (RBBB/LBBB) on post-TAVI PPI. We performed a systematic literature review to identify studies reporting on RBBB and/or LBBB status and post-TAVI PPI. Study design, patient characteristics, and the presence of branch block were analyzed. Odds ratios (ORs) with 95% CI were extracted. The final analysis included 36 studies, reporting about 55,851 patients. Data on LBBB were extracted from 33 studies. Among 51,026 patients included, 5503 showed pre-implant LBBB (11.9% (10.4%-13.8%)). The influence of LBBB on post-TAVI PPI was not significant OR 1.1474 (0.9025; 1.4588),

Keywords: left bundle branch block; permanent pacemaker implantation; right bundle branch block; transcatheter aortic valve implantation

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