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Sahana J, Corydon TJ, Wehland M, et al. Alterations of Growth and Focal Adhesion Molecules in Human Breast Cancer Cells Exposed to the Random Positioning Machine. Front Cell Dev Biol. 2021;9:672098doi: 10.3389/fcell.2021.672098.
Sahana, J., Corydon, T. J., Wehland, M., Krüger, M., Kopp, S., Melnik, D., Kahlert, S., Relja, B., Infanger, M., & Grimm, D. (2021). Alterations of Growth and Focal Adhesion Molecules in Human Breast Cancer Cells Exposed to the Random Positioning Machine. Frontiers in cell and developmental biology, 9672098. https://doi.org/10.3389/fcell.2021.672098
Sahana, Jayashree, et al. "Alterations of Growth and Focal Adhesion Molecules in Human Breast Cancer Cells Exposed to the Random Positioning Machine." Frontiers in cell and developmental biology vol. 9 (2021): 672098. doi: https://doi.org/10.3389/fcell.2021.672098
Sahana J, Corydon TJ, Wehland M, Krüger M, Kopp S, Melnik D, Kahlert S, Relja B, Infanger M, Grimm D. Alterations of Growth and Focal Adhesion Molecules in Human Breast Cancer Cells Exposed to the Random Positioning Machine. Front Cell Dev Biol. 2021 Jun 30;9:672098. doi: 10.3389/fcell.2021.672098. eCollection 2021. PMID: 34277614; PMCID: PMC8278480.
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Front Cell Dev Biol. 2021 Jun 30;9:672098. doi: 10.3389/fcell.2021.672098. eCollection 2021.

Alterations of Growth and Focal Adhesion Molecules in Human Breast Cancer Cells Exposed to the Random Positioning Machine.

Frontiers in cell and developmental biology

Jayashree Sahana, Thomas J Corydon, Markus Wehland, Marcus Krüger, Sascha Kopp, Daniela Melnik, Stefan Kahlert, Borna Relja, Manfred Infanger, Daniela Grimm

Affiliations

  1. Department of Biomedicine, Aarhus University, Aarhus, Denmark.
  2. Department of Ophthalmology, Aarhus University Hospital, Aarhus, Denmark.
  3. Department of Microgravity and Translational Regenerative Medicine, Clinic for Plastic, Aesthetic and Hand Surgery, Otto von Guericke University, Magdeburg, Germany.
  4. Research Group "Magdeburger Arbeitsgemeinschaft für Forschung unter Raumfahrt- und Schwerelosigkeitsbedingungen" (MARS), Otto von Guericke University, Magdeburg, Germany.
  5. Institute of Anatomy, Otto von Guericke University, Magdeburg, Germany.
  6. Department of Radiology and Nuclear Medicine, Experimental Radiology, Otto von Guericke University, Magdeburg, Germany.

PMID: 34277614 PMCID: PMC8278480 DOI: 10.3389/fcell.2021.672098

Abstract

In this study, we evaluated changes in focal adhesions (FAs) in two types of breast cancer cell (BCC) lines (differentiated MCF-7 and the triple-negative MDA-MB-231 cell line) exposed to simulated microgravity (s-μ

Copyright © 2021 Sahana, Corydon, Wehland, Krüger, Kopp, Melnik, Kahlert, Relja, Infanger and Grimm.

Keywords: breast cancer; cytoskeleton; extracellular matrix; focal adhesions; microgravity; multicellular spheroids

Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. The reviewer RH declared a

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