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Rodríguez J, Prieto S, Laguado E, et al. Application of a Diagnostic Methodology of Cardiac Systems Based on the Proportions of Entropy in Normal Patients and with Different Pathologies. Pulse (Basel). 2021;8(3):114-119doi: 10.1159/000515699.
Rodríguez, J., Prieto, S., Laguado, E., Pernett, F., Villamizar, M., Olivella, E., Angarita, F., de la Cruz, G., Morales, C., & Castro, M. (2021). Application of a Diagnostic Methodology of Cardiac Systems Based on the Proportions of Entropy in Normal Patients and with Different Pathologies. Pulse (Basel, Switzerland), 8(3), 114-119. https://doi.org/10.1159/000515699
Rodríguez, Javier, et al. "Application of a Diagnostic Methodology of Cardiac Systems Based on the Proportions of Entropy in Normal Patients and with Different Pathologies." Pulse (Basel, Switzerland) vol. 8,3 (2021): 114-119. doi: https://doi.org/10.1159/000515699
Rodríguez J, Prieto S, Laguado E, Pernett F, Villamizar M, Olivella E, Angarita F, de la Cruz G, Morales C, Castro M. Application of a Diagnostic Methodology of Cardiac Systems Based on the Proportions of Entropy in Normal Patients and with Different Pathologies. Pulse (Basel). 2021 Jun;8(3):114-119. doi: 10.1159/000515699. Epub 2021 May 12. PMID: 34307208; PMCID: PMC8280414.
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Pulse (Basel). 2021 Jun;8(3):114-119. doi: 10.1159/000515699. Epub 2021 May 12.

Application of a Diagnostic Methodology of Cardiac Systems Based on the Proportions of Entropy in Normal Patients and with Different Pathologies.

Pulse (Basel, Switzerland)

Javier Rodríguez, Signed Prieto, Elveny Laguado, Frank Pernett, Magda Villamizar, Edinson Olivella, Fredy Angarita, Giovanni de la Cruz, Carlos Morales, Mónica Castro

Affiliations

  1. Research Department, Hospital Universitario Nacional de Colombia, Bogotá, Colombia.
  2. Research Department, Insight Research Group SAS, Bogotá, Colombia.
  3. Faculty of Nursery, Universidad Cooperativa de Colombia, Bucaramanga, Colombia.
  4. Critical Care Unit, Clínica del Country, Bogotá, Colombia.
  5. Clínica de Girón, Santander, Colombia.
  6. Faculty of Engineering, Universidad Cooperativa de Colombia, Bucaramanga, Colombia.

PMID: 34307208 PMCID: PMC8280414 DOI: 10.1159/000515699

Abstract

INTRODUCTION: Dynamical systems theory, probability, and entropy were the substrate for the development of the diagnostic and predictive methodology of adult heart dynamics.

OBJECTIVE: To apply a previously developed methodology from dynamical systems, probability, and entropy in both normal and pathological subjects.

METHODS: Electrocardiographic records were selected from 30 healthy subjects and 200 with different pathologies, with a length of least 18 h. Numerical attractors from dynamical attractors and the probability of occurrence of ordered pairs of consecutive heart rates were built. A calculation of entropy and its proportions was performed and statistical analysis was conducted.

RESULTS: The normal patients' heart dynamics were evaluated according to the methodology of entropy proportions, highlighting that there are differences in normal patients with different pathologies. There was maximal level of sensitivity, specificity, and diagnostic agreement.

CONCLUSION: Proportional entropy constitutes a diagnostic and predictive method of heart systems, and may be useful as a tool to objectively diagnose and perform the follow-up of normal and pathological cases.

Copyright © 2021 by S. Karger AG, Basel.

Keywords: Entropy; Heart dynamics; Heart rate; Holter; Nonlinear dynamics

Conflict of interest statement

The authors have no conflicts of interest to declare.

References

  1. J Surg Res. 2018 Apr;224:64-71 - PubMed
  2. PLoS One. 2017 Jun 27;12(6):e0180060 - PubMed
  3. Nat Rev Cardiol. 2017 Jan;14(1):56-64 - PubMed
  4. Proc Natl Acad Sci U S A. 2002 Feb 19;99 Suppl 1:2466-72 - PubMed
  5. BMC Med Phys. 2010 Sep 17;10:1 - PubMed
  6. Circulation. 2000 Jan 4-11;101(1):47-53 - PubMed
  7. Phys Rev E. 2018 Apr;97(4-1):042414 - PubMed
  8. Philos Trans A Math Phys Eng Sci. 2009 Jan 28;367(1887):277-96 - PubMed
  9. Clin Exp Hypertens. 2005 Feb-Apr;27(2-3):149-58 - PubMed

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