Display options
Cite
Kam KW, Wong CH, Ho M, et al. Iris Depigmentation in the Prediction of Cytomegalovirus Anterior Uveitis. Ocul Immunol Inflamm. 2021;1-6doi: 10.1080/09273948.2021.1952277.
Kam, K. W., Wong, C. H., Ho, M., Sze, R. K. H., Chan, P. K. S., & Young, A. L. (2021). Iris Depigmentation in the Prediction of Cytomegalovirus Anterior Uveitis. Ocular immunology and inflammation, 1-6. https://doi.org/10.1080/09273948.2021.1952277
Kam, Ka Wai, et al. "Iris Depigmentation in the Prediction of Cytomegalovirus Anterior Uveitis." Ocular immunology and inflammation vol. (2021): 1-6. doi: https://doi.org/10.1080/09273948.2021.1952277
Kam KW, Wong CH, Ho M, Sze RKH, Chan PKS, Young AL. Iris Depigmentation in the Prediction of Cytomegalovirus Anterior Uveitis. Ocul Immunol Inflamm. 2021 Jul 20;1-6. doi: 10.1080/09273948.2021.1952277. Epub 2021 Jul 20. PMID: 34283680.
Copy Download .nbib Format: NLM
Share it on

Ocul Immunol Inflamm. 2021 Jul 20;1-6. doi: 10.1080/09273948.2021.1952277. Epub 2021 Jul 20.

Iris Depigmentation in the Prediction of Cytomegalovirus Anterior Uveitis.

Ocular immunology and inflammation

Ka Wai Kam, Chung Hei Wong, Mary Ho, Ryan Kin Ho Sze, Paul K S Chan, Alvin L Young

Affiliations

  1. Department of Ophthalmology & Visual Sciences, The Chinese University of Hong Kong, Hong Kong, Hong Kong.
  2. Department of Ophthalmology & Visual Sciences, Prince of Wales Hospital, Hong Kong, Hong Kong.
  3. Department of Microbiology, The Chinese University of Hong Kong, Hong Kong, Hong Kong.

PMID: 34283680 DOI: 10.1080/09273948.2021.1952277

Abstract

PURPOSE: We hypothesize that the presence of iris depigmentation is associated with the prediction of cytomegalovirus (CMV) as the etiology of chronic or recurrent anterior uveitis.

METHODS: A prospective cohort study on patients with recurrent or chronic anterior uveitis. Pre-operative data on iris depigmentation and corneal endothelial cell densities were compared between eyes with and without CMV.

RESULTS: Forty-one eyes of 38 subjects with a mean age of 61.1 ± 11.2 years old were recruited. Seventeen eyes were positive for CMV. A greater proportion of eyes with CMV showed severe or diffuse iris depigmentation than eyes without CMV, and possessed larger corneal endothelial cells (

CONCLUSION: Iris depigmentation is a potential clinical biomarker in predicting CMV in chronic or recurrent anterior uveitis.

Keywords: Cornea; cytomegalovirus; endotheliitis; glaucoma; uveitis

Publication Types