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Clin Nucl Med. 2021 Jul 20; doi: 10.1097/RLU.0000000000003833. Epub 2021 Jul 20.

Hypertrophic Pachymeningitis Demonstrated by Whole-Body 67Ga Scintigraphy.

Clinical nuclear medicine

Shiro Ishii, Shigeyasu Sugawara, Ryo Yamakuni, Hirofumi Sekino, Hiroshi Ito

Affiliations

  1. From the Department of Radiology, Fukushima Medical University, Fukushima, Japan.

PMID: 34284475 DOI: 10.1097/RLU.0000000000003833

Abstract

ABSTRACT: Hypertrophic pachymeningitis is a rare inflammatory process characterized by thickening of the dura mater that can be idiopathic or secondary to a variety of conditions such as ANCA-related vasculitis, IgG4-related disease, Sjögren syndrome, rheumatoid arthritis, sarcoidosis, and infections. It can cause various neurological alterations such as headache, cranial nerve disorder, cerebellar disorder, sensory impairment, and weakness. Brain MRI is useful for imaging diagnosis of hypertrophic pachymeningitis, showing focal thickening and enhancement of the dura mater. Here we report 4 cases of idiopathic hypertrophic pachymeningitis where 67Ga clearly accumulated in the dura mater.

Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.

Conflict of interest statement

Conflicts of interest and sources of funding: none declared.

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