Display options
Cite
Pratomo IP, Noor DR, Kusmardi K, et al. Xanthine Oxidase-Induced Inflammatory Responses in Respiratory Epithelial Cells: A Review in Immunopathology of COVID-19. Int J Inflam. 2021;2021:1653392doi: 10.1155/2021/1653392.
Pratomo, I. P., Noor, D. R., Kusmardi, K., Rukmana, A., Paramita, R. I., Erlina, L., Fadilah, F., Gayatri, A., Fitriani, M., Purnomo, T. T. H., Ariane, A., Heryanto, R., & Tedjo, A. (2021). Xanthine Oxidase-Induced Inflammatory Responses in Respiratory Epithelial Cells: A Review in Immunopathology of COVID-19. International journal of inflammation, 20211653392. https://doi.org/10.1155/2021/1653392
Pratomo, Irandi Putra, et al. "Xanthine Oxidase-Induced Inflammatory Responses in Respiratory Epithelial Cells: A Review in Immunopathology of COVID-19." International journal of inflammation vol. 2021 (2021): 1653392. doi: https://doi.org/10.1155/2021/1653392
Pratomo IP, Noor DR, Kusmardi K, Rukmana A, Paramita RI, Erlina L, Fadilah F, Gayatri A, Fitriani M, Purnomo TTH, Ariane A, Heryanto R, Tedjo A. Xanthine Oxidase-Induced Inflammatory Responses in Respiratory Epithelial Cells: A Review in Immunopathology of COVID-19. Int J Inflam. 2021 Aug 05;2021:1653392. doi: 10.1155/2021/1653392. eCollection 2021. PMID: 34367545; PMCID: PMC8346299.
Copy Download .nbib Format: NLM
Share it on

Int J Inflam. 2021 Aug 05;2021:1653392. doi: 10.1155/2021/1653392. eCollection 2021.

Xanthine Oxidase-Induced Inflammatory Responses in Respiratory Epithelial Cells: A Review in Immunopathology of COVID-19.

International journal of inflammation

Irandi Putra Pratomo, Dimas R Noor, Kusmardi Kusmardi, Andriansjah Rukmana, Rafika I Paramita, Linda Erlina, Fadilah Fadilah, Anggi Gayatri, Magna Fitriani, Tommy T H Purnomo, Anna Ariane, Rudi Heryanto, Aryo Tedjo

Affiliations

  1. Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia.
  2. COVID-19 Task Force-Pulmonology and Respiratory Medicine Unit, Universitas Indonesia University Hospital, Universitas Indonesia, Depok, Indonesia.
  3. Bioinformatics Core Facilities, Indonesian Medical Education and Research Institute, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia.
  4. Human Cancer Research Center, Indonesian Medical Education and Research Institute, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia.
  5. Department of Pathology Anatomy, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia.
  6. Drug Development Research Cluster, Indonesian Medical Education and Research Institute, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia.
  7. Department of Microbiology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia.
  8. Department of Medical Chemistry, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia.
  9. Master's Programme in Biomedical Sciences, Faculty of Medicine, Universitas Indonesia, DKI Jakarta, Depok, Indonesia.
  10. Department of Pharmacology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia.
  11. Universitas Indonesia University Hospital, Universitas Indonesia, Depok, Indonesia.
  12. Division of Rheumatology, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia-Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia.
  13. Department of Chemistry, Faculty of Mathematics and Natural Sciences, IPB University, Bogor, Indonesia.
  14. Tropical Biopharmaca Research Center, IPB University, Bogor, Indonesia.

PMID: 34367545 PMCID: PMC8346299 DOI: 10.1155/2021/1653392

Abstract

Xanthine oxidase (XO) is an enzyme that catalyzes the production of uric acid and superoxide radicals from purine bases: hypoxanthine and xanthine and is also expressed in respiratory epithelial cells. Uric acid, which is also considered a danger associated molecule pattern (DAMP), could trigger a series of inflammatory responses by activating the inflammasome complex path and NF-

Copyright © 2021 Irandi Putra Pratomo et al.

Conflict of interest statement

The authors declare that they have no conflicts of interest.

References

  1. Indian J Crit Care Med. 2016 Sep;20(9):518-25 - PubMed
  2. Science. 2020 Nov 13;370(6518):861-865 - PubMed
  3. Hippokratia. 2013 Apr;17(2):141-5 - PubMed
  4. Arterioscler Thromb Vasc Biol. 2009 Nov;29(11):1787-93 - PubMed
  5. Arthritis Res Ther. 2013;15(5):118 - PubMed
  6. Vascul Pharmacol. 2018 Jan;100:1-19 - PubMed
  7. J Intensive Care Med. 2019 May;34(5):404-410 - PubMed
  8. Diabetes. 2002 Apr;51(4):1118-24 - PubMed
  9. J Clin Invest. 2020 May 1;130(5):2620-2629 - PubMed
  10. Am J Respir Crit Care Med. 2010 Sep 15;182(6):774-83 - PubMed
  11. Sci Rep. 2017 Jan 13;7:39884 - PubMed
  12. Pulm Med. 2020 Aug 10;2020:6175964 - PubMed
  13. Free Radic Res. 2005 Jul;39(7):755-62 - PubMed
  14. Circulation. 2020 Jun 2;141(22):1736-1738 - PubMed
  15. Biochim Biophys Acta. 2009 Apr;1788(4):864-71 - PubMed
  16. Blood. 2020 Sep 3;136(10):1169-1179 - PubMed
  17. J Biol Chem. 1997 Nov 7;272(45):28335-41 - PubMed
  18. J Clin Invest. 2018 Nov 1;128(11):5178-5183 - PubMed
  19. Mol Med Rep. 2016 May;13(5):4343-8 - PubMed
  20. Int J Rheum Dis. 2018 Sep;21(9):1723-1727 - PubMed
  21. Nature. 2006 Mar 9;440(7081):237-41 - PubMed
  22. Redox Biol. 2013 Jun 10;1:353-8 - PubMed
  23. Proc Natl Acad Sci U S A. 2000 Sep 26;97(20):10723-8 - PubMed
  24. Clin Chem Lab Med. 2020 Jun 25;58(7):1131-1134 - PubMed
  25. Cancer Immunol Immunother. 1992;35(6):421-5 - PubMed
  26. Circulation. 2002 Jul 9;106(2):221-6 - PubMed
  27. Cell Death Dis. 2019 Apr 25;10(5):346 - PubMed
  28. Pain. 2021 Jan;162(1):243-252 - PubMed
  29. FASEB J. 2015 Oct;29(10):4162-73 - PubMed
  30. Evid Based Med. 2012 Aug;17(4):105-8 - PubMed
  31. Cell Mol Life Sci. 2011 Jan;68(1):151-8 - PubMed
  32. Circulation. 2020 Jul 7;142(1):68-78 - PubMed
  33. J Biosci. 2003 Feb;28(1):95-100 - PubMed
  34. Forensic Sci Med Pathol. 2021 Jun;17(2):279-296 - PubMed
  35. Respir Res. 2020 Jul 28;21(1):198 - PubMed
  36. Science. 2004 Mar 5;303(5663):1532-5 - PubMed
  37. Free Radic Res. 2001 Dec;35(6):665-79 - PubMed
  38. Radiol Cardiothorac Imaging. 2020 Jun 18;2(3):e200277 - PubMed
  39. Free Radic Biol Med. 2006 Mar 15;40(6):952-9 - PubMed
  40. Mucosal Immunol. 2020 Jul;13(4):691-701 - PubMed
  41. Int J Infect Dis. 2005 Nov;9(6):323-30 - PubMed
  42. J Immunol. 2015 Feb 15;194(4):1776-87 - PubMed
  43. J Biol Chem. 1999 Feb 19;274(8):4985-94 - PubMed
  44. J Leukoc Biol. 2009 Nov;86(5):1145-51 - PubMed
  45. Kidney Int. 2020 Nov;98(5):1296-1307 - PubMed
  46. Free Radic Res. 2004 Sep;38(9):919-25 - PubMed
  47. Lancet. 2020 Feb 15;395(10223):497-506 - PubMed
  48. J Immunol Res. 2017;2017:6710278 - PubMed
  49. Sci Rep. 2017 Feb 15;7:42341 - PubMed
  50. Thromb Haemost. 2017 Oct 5;117(10):1919-1929 - PubMed
  51. Am J Kidney Dis. 2005 Jan;45(1):88-95 - PubMed
  52. J Intensive Care. 2013 Dec 04;1(1):13 - PubMed
  53. Eur Respir J. 2020 Jul 30;56(1): - PubMed
  54. Clin Exp Pharmacol Physiol. 2008 Apr;35(4):420-5 - PubMed
  55. BMC Nephrol. 2019 Aug 14;20(1):319 - PubMed
  56. Int J Mol Sci. 2015 Dec 04;16(12):29029-46 - PubMed
  57. Rev Med Chir Soc Med Nat Iasi. 2014 Oct-Dec;118(4):942-5 - PubMed
  58. Proc Natl Acad Sci U S A. 2003 Jul 8;100(14):8170-5 - PubMed
  59. J Clin Invest. 2006 Aug;116(8):2262-71 - PubMed
  60. Sci Rep. 2020 Nov 12;10(1):19630 - PubMed
  61. J Biol Chem. 2008 Oct 17;283(42):28595-606 - PubMed
  62. Viruses. 2018 Jul 26;10(8): - PubMed
  63. Front Endocrinol (Lausanne). 2021 May 06;12:633767 - PubMed
  64. Mol Med. 2016 Oct;22:621-631 - PubMed
  65. Biomed Res Int. 2017;2017:4391920 - PubMed
  66. Shock. 2010 Dec;34(6):601-7 - PubMed
  67. Scand J Immunol. 2021 Feb;93(2):e12960 - PubMed
  68. Gastroenterology. 1981 Jul;81(1):22-9 - PubMed
  69. Nat Rev Immunol. 2021 Jan;21(1):49-64 - PubMed

Publication Types