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Verbeure W, Geeraerts A, Huang IH, et al. The effect of an air purifier on aerosol generation measurements during clinical motility testing. Neurogastroenterol Motil. 2021;e14227doi: 10.1111/nmo.14227.
Verbeure, W., Geeraerts, A., Huang, I. H., Timmermans, L., Tóth, J., Geysen, H., Cools, L., Carbone, F., Schol, J., Devriese, H., Haesaerts, R., Mori, H., Vanuytsel, T., & Tack, J. (2021). The effect of an air purifier on aerosol generation measurements during clinical motility testing. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, e14227. https://doi.org/10.1111/nmo.14227
Verbeure, Wout, et al. "The effect of an air purifier on aerosol generation measurements during clinical motility testing." Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society vol. (2021): e14227. doi: https://doi.org/10.1111/nmo.14227
Verbeure W, Geeraerts A, Huang IH, Timmermans L, Tóth J, Geysen H, Cools L, Carbone F, Schol J, Devriese H, Haesaerts R, Mori H, Vanuytsel T, Tack J. The effect of an air purifier on aerosol generation measurements during clinical motility testing. Neurogastroenterol Motil. 2021 Aug 02;e14227. doi: 10.1111/nmo.14227. Epub 2021 Aug 02. PMID: 34342092; PMCID: PMC8420584.
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Neurogastroenterol Motil. 2021 Aug 02;e14227. doi: 10.1111/nmo.14227. Epub 2021 Aug 02.

The effect of an air purifier on aerosol generation measurements during clinical motility testing.

Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society

Wout Verbeure, Annelies Geeraerts, I-Hsuan Huang, Lien Timmermans, Joran Tóth, Hannelore Geysen, Louise Cools, Florencia Carbone, Jolien Schol, Herman Devriese, Rico Haesaerts, Hideki Mori, Tim Vanuytsel, Jan Tack

Affiliations

  1. Translational Research Center for Gastrointestinal Disorders, KU Leuven, Leuven, Belgium.
  2. Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
  3. Neurogastroenterology and motility, University Hospitals Leuven, Leuven, Belgium.
  4. Prevention and Environment, University Hospitals Leuven, Leuven, Belgium.

PMID: 34342092 PMCID: PMC8420584 DOI: 10.1111/nmo.14227

Abstract

BACKGROUND: Aerosol spread is key to interpret the risk of viral contamination during clinical procedures such as esophageal high-resolution manometry (HRM). Installing an air purifier seems a legitimate strategy, but this has recently been questioned.

METHODS: Patients undergoing an HRM procedure at the Leuven University Hospital were included in this clinical study. All subjects had to wear a surgical mask which was only lowered beneath the nose during the placement and removal of the nasogastric catheter. The number of aerosol particles was measured by a Lasair

KEY RESULTS: Thirteen patients underwent a manometry examination. The amount of 0.3 µm-sized particles was unaffected during the whole procedure. The larger particle sizes (1.0; 3.0; 5.0; and 10.0 µm) decreased when the catheter was positioned, but not 0.5 µm. During the HRM measurements itself, these numbers decreased further. Yet, 1 min after catheter removal a significant elevation of particles was seen, which did not recover within 5 min.

CONCLUSIONS & INTERFERENCES: Based on this study, there is no evidence that filtration systems reduce aerosol particles properly during a clinical investigation.

© 2021 John Wiley & Sons Ltd.

Keywords: COVID19; aerosol; air purifier; nasogastric intubation

References

  1. Neurogastroenterol Motil. 2021 Aug 2;:e14227 - PubMed
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  4. N Engl J Med. 2020 Apr 16;382(16):1564-1567 - PubMed
  5. Gut. 2020 Dec 31;: - PubMed
  6. Neurogastroenterol Motil. 2020 Jul;32(7):e13930 - PubMed

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