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Watanabe Y, Hayashi K, Terai S. A Rare Case of Ulcerative Colitis with Severe Pneumocystis jirovecii Pneumonia and Cytomegalovirus Colitis: A Case Report and Literature Review. Intern Med. 2021;doi: 10.2169/internalmedicine.7953-21.
Watanabe, Y., Hayashi, K., & Terai, S. (2021). A Rare Case of Ulcerative Colitis with Severe Pneumocystis jirovecii Pneumonia and Cytomegalovirus Colitis: A Case Report and Literature Review. Internal medicine (Tokyo, Japan), . https://doi.org/10.2169/internalmedicine.7953-21
Watanabe, Yusuke, et al. "A Rare Case of Ulcerative Colitis with Severe Pneumocystis jirovecii Pneumonia and Cytomegalovirus Colitis: A Case Report and Literature Review." Internal medicine (Tokyo, Japan) vol. (2021). doi: https://doi.org/10.2169/internalmedicine.7953-21
Watanabe Y, Hayashi K, Terai S. A Rare Case of Ulcerative Colitis with Severe Pneumocystis jirovecii Pneumonia and Cytomegalovirus Colitis: A Case Report and Literature Review. Intern Med. 2021 Aug 06; doi: 10.2169/internalmedicine.7953-21. Epub 2021 Aug 06. PMID: 34373380.
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Intern Med. 2021 Aug 06; doi: 10.2169/internalmedicine.7953-21. Epub 2021 Aug 06.

A Rare Case of Ulcerative Colitis with Severe Pneumocystis jirovecii Pneumonia and Cytomegalovirus Colitis: A Case Report and Literature Review.

Internal medicine (Tokyo, Japan)

Yusuke Watanabe, Kazunao Hayashi, Shuji Terai

Affiliations

  1. Division of Preemptive Medicine for Digestive Disease and Healthy Active Life, School of Medicine, Niigata University, Japan.
  2. Division of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences, Niigata University, Japan.
  3. Department of Preventive and Minimally Invasive Medicine for Digestive Desease, Niigata University, Japan.

PMID: 34373380 DOI: 10.2169/internalmedicine.7953-21

Abstract

Pneumocystis jirovecii pneumonia (PJP) and cytomegalovirus (CMV) colitis are opportunistic infections that occur during immunosuppressive treatments for ulcerative colitis (UC). The prognosis of PJP and CMV colitis is very poor. We herein report a rare case of a 74-year-old UC patient with PJP and CMV colitis that was successfully treated with intensive therapy. PJP progresses rapidly, so the timing and choice of treatment are critical. Furthermore, a literature review of similar cases suggested that prophylactic therapy for opportunistic infections might be important, especially in the elderly. This case will serve as a reference for successful treatment in future cases.

Keywords: Pneumocystis jirovecii pneumonia; cytomegalovirus colitis; immunosuppressive agent; prophylactic therapy; ulcerative colitis

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