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Front Cell Dev Biol. 2021 Jul 19;9:703603. doi: 10.3389/fcell.2021.703603. eCollection 2021.

A Small Molecule Inhibitor of Pex3-Pex19 Interaction Disrupts Glycosome Biogenesis and Causes Lethality in .

Frontiers in cell and developmental biology

Hiren Banerjee, Paul LaPointe, Gary Eitzen, Richard A Rachubinski

Affiliations

  1. Department of Cell Biology, University of Alberta, Edmonton, AB, Canada.

PMID: 34350186 PMCID: PMC8326762 DOI: 10.3389/fcell.2021.703603

Abstract

Trypanosomatid parasites, including

Copyright © 2021 Banerjee, LaPointe, Eitzen and Rachubinski.

Keywords: drug screening; glycosome; neglected tropical disease; organelle biogenesis; protein–protein interaction; small molecule inhibitor; trypanosome; yeast two-hybrid

Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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