Display options
Share it on

Toxicon X. 2021 Jul 17;9:100074. doi: 10.1016/j.toxcx.2021.100074. eCollection 2021 Jul.

Chronic health effects and cost of snakebite.

Toxicon: X

Anuradhani Kasturiratne, David G Lalloo, H Janaka de Silva

Affiliations

  1. Faculty of Medicine, University of Kelaniya, Ragama, Sri Lanka.
  2. Liverpool School of Tropical Medicine, UK.

PMID: 34355162 PMCID: PMC8321925 DOI: 10.1016/j.toxcx.2021.100074

Abstract

The burden of disability among survivors and the socio-economic impact of snakebite have not been adequately researched. We reviewed original research articles, case reports and small case series relating to chronic physical, mental and psycho-social disability and economic burden of snakebite. Both physical and psychological health problems seem common in snakebite survivors and can lead to disability and loss of productivity. Chronic physical health effects, musculoskeletal disability being the commonest, can be largely attributed to limited and delayed access to optimal treatment of acute envenoming. The economic burden is considerable, and includes health system costs, out-of-pocket expenditure and opportunity costs, with regional variations. Health systems should be more responsive to needs and circumstances of bite victims, and a more holistic approach should be developed in the treatment of snakebite which incorporates the management of chronic health effects.

© 2021 The Authors.

Keywords: Chronic health effects; Cost; Physical disability; Psychological effects; Snakebite; Socio-economic burden

Conflict of interest statement

All three authors have no conflict of interests to declare.

References

  1. BMJ. 2021 Mar 29;372:n71 - PubMed
  2. PLoS Negl Trop Dis. 2017 Nov 6;11(11):e0006073 - PubMed
  3. Hand Surg. 2015;20(2):330-2 - PubMed
  4. Neurol India. 2018 Sep-Oct;66(5):1351-1358 - PubMed
  5. Saudi Pharm J. 2020 Aug;28(8):1049-1054 - PubMed
  6. PLoS Negl Trop Dis. 2011 Aug;5(8):e1255 - PubMed
  7. PLoS Negl Trop Dis. 2019 Jun 24;13(6):e0007551 - PubMed
  8. Anaesth Intensive Care. 1998 Oct;26(5):584-5 - PubMed
  9. Wilderness Environ Med. 2008 Winter;19(4):267-74 - PubMed
  10. Mil Med. 2005 Apr;170(4):342-8 - PubMed
  11. Ann Trop Med Parasitol. 2010 Jul;104(5):439-48 - PubMed
  12. Rev Soc Bras Med Trop. 2019 Jul 18;52:e20190115 - PubMed
  13. Wilderness Environ Med. 2021 Mar;32(1):78-82 - PubMed
  14. J Hand Surg Am. 2021 May 25;: - PubMed
  15. PLoS One. 2013 Nov 21;8(11):e80090 - PubMed
  16. QJM. 2021 Jul 28;114(4):255-257 - PubMed
  17. PLoS Negl Trop Dis. 2015 Sep 23;9(9):e0004088 - PubMed
  18. BMJ Paediatr Open. 2020 Sep 16;4(1):e000735 - PubMed
  19. Trop Doct. 1998 Oct;28(4):223-6 - PubMed
  20. Int J Psychiatry Med. 2021 Mar;56(2):97-115 - PubMed
  21. J Pediatr Surg. 1998 Nov;33(11):1593-5 - PubMed
  22. Cureus. 2018 Nov 12;10(11):e3574 - PubMed
  23. PLoS Negl Trop Dis. 2016 Mar 30;10(3):e0004568 - PubMed
  24. Trop Doct. 2012 Jan;42(1):41-3 - PubMed
  25. Wilderness Environ Med. 2020 Dec;31(4):470-481 - PubMed
  26. PLoS Negl Trop Dis. 2009 Dec 22;3(12):e569 - PubMed
  27. Wilderness Environ Med. 2018 Dec;29(4):437-445 - PubMed
  28. Indian J Med Res. 2017 Dec;146(6):754-758 - PubMed
  29. Toxicon. 2018 Feb;142:34-41 - PubMed
  30. Ann Trop Med Parasitol. 1980 Oct;74(5):523-30 - PubMed
  31. Toxicon. 2021 Apr 15;193:1-3 - PubMed
  32. Am J Surg. 2006 Dec;192(6):848-52 - PubMed
  33. J Postgrad Med. 2002 Oct-Dec;48(4):275-8; discussion 278-9 - PubMed
  34. Trans R Soc Trop Med Hyg. 2020 Sep 1;114(9):635-642 - PubMed
  35. Trans R Soc Trop Med Hyg. 2010 May;104(5):351-6 - PubMed
  36. Toxins (Basel). 2020 Jan 11;12(1): - PubMed
  37. Clin Kidney J. 2019 Jun 03;13(4):564-570 - PubMed
  38. Am J Trop Med Hyg. 2004 Aug;71(2):234-8 - PubMed
  39. BMC Pulm Med. 2020 Feb 7;20(1):35 - PubMed
  40. Southeast Asian J Trop Med Public Health. 2005 May;36(3):733-40 - PubMed
  41. F1000Res. 2019 Sep 4;8:1588 - PubMed
  42. PLoS Negl Trop Dis. 2018 Jul 9;12(7):e0006643 - PubMed
  43. PLoS Negl Trop Dis. 2016 Nov 4;10(11):e0005103 - PubMed
  44. Nephrol Dial Transplant. 2009 Mar;24(3):829-33 - PubMed
  45. PLoS Negl Trop Dis. 2021 Apr 16;15(4):e0009298 - PubMed
  46. J Venom Anim Toxins Incl Trop Dis. 2020 Dec 14;26:e20200083 - PubMed
  47. Toxicon. 2018 Aug;150:115-123 - PubMed
  48. Toxicon. 2012 Jul;60(1):61-5 - PubMed
  49. Clin Toxicol (Phila). 2021 Sep;59(9):794-800 - PubMed
  50. Hosp Pediatr. 2014 Sep;4(5):276-82 - PubMed
  51. Clinicoecon Outcomes Res. 2020 Sep 18;12:547-554 - PubMed
  52. Ochsner J. 2021 Spring;21(1):90-92 - PubMed
  53. Saudi J Biol Sci. 2017 Feb;24(2):362-366 - PubMed
  54. Wilderness Environ Med. 2014 Jun;25(2):210-3 - PubMed
  55. PLoS Med. 2008 Nov 4;5(11):e218 - PubMed
  56. Trans R Soc Trop Med Hyg. 2021 Jun 2;115(6):613-618 - PubMed
  57. Trans R Soc Trop Med Hyg. 1994 Jan-Feb;88(1):81-5 - PubMed
  58. PLoS Negl Trop Dis. 2020 Jun 25;14(6):e0008334 - PubMed
  59. Am J Trop Med Hyg. 2021 Apr 5;: - PubMed
  60. Wilderness Environ Med. 2020 Sep;31(3):337-343 - PubMed
  61. Toxicon. 2012 Sep 15;60(4):706-11 - PubMed
  62. Toxins (Basel). 2019 Mar 31;11(4): - PubMed
  63. Clin Neurol Neurosurg. 2005 Dec;108(1):45-7 - PubMed
  64. Orthopedics. 2010 Jul 13;33(7):515 - PubMed
  65. PLoS Negl Trop Dis. 2017 Jul 6;11(7):e0005647 - PubMed
  66. Medicine (Baltimore). 2021 Jan 22;100(3):e24290 - PubMed
  67. Wilderness Environ Med. 2020 Sep;31(3):317-323 - PubMed
  68. Ann Trop Med Parasitol. 1994 Dec;88(6):665-71 - PubMed
  69. Int J Gen Med. 2018 Jun 05;11:209-216 - PubMed
  70. BMC Res Notes. 2017 Aug 14;10(1):405 - PubMed
  71. Med Sci Monit. 2019 Jun 17;25:4495-4502 - PubMed
  72. J Multidiscip Healthc. 2018 Jun 26;11:279-285 - PubMed
  73. PLoS One. 2019 Mar 5;14(3):e0213077 - PubMed
  74. J Coll Physicians Surg Pak. 2016 Jun;26(6):517-20 - PubMed
  75. Toxicon. 2019 Mar 1;159:1-4 - PubMed
  76. Biomedica. 2020 Dec 02;40(4):609-615 - PubMed
  77. Postgrad Med J. 2002 May;78(919):276-80 - PubMed
  78. Arch Public Health. 2020 Jun 19;78:59 - PubMed
  79. Q J Med. 1990 Apr;75(276):399-411 - PubMed
  80. Pharmacotherapy. 2012 May;32(5):433-40 - PubMed
  81. PLoS Negl Trop Dis. 2015 Aug 11;9(8):e0003989 - PubMed
  82. Pituitary. 2014 Apr;17(2):125-31 - PubMed

Publication Types