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Gowda J, Tavarageri A, Kulkarni R, et al. Comparative Assessment of the Antimicrobial Efficacy of Triclosan, Amoxicillin and Eugenol against . Int J Clin Pediatr Dent. 2021;14(1):59-62doi: 10.5005/jp-journals-10005-1869.
Gowda, J., Tavarageri, A., Kulkarni, R., Anegundi, R. T., Janardhan, A., & Bhat, M. A. (2021). Comparative Assessment of the Antimicrobial Efficacy of Triclosan, Amoxicillin and Eugenol against . International journal of clinical pediatric dentistry, 14(1), 59-62. https://doi.org/10.5005/jp-journals-10005-1869
Gowda, Jagadish, et al. "Comparative Assessment of the Antimicrobial Efficacy of Triclosan, Amoxicillin and Eugenol against ." International journal of clinical pediatric dentistry vol. 14,1 (2021): 59-62. doi: https://doi.org/10.5005/jp-journals-10005-1869
Gowda J, Tavarageri A, Kulkarni R, Anegundi RT, Janardhan A, Bhat MA. Comparative Assessment of the Antimicrobial Efficacy of Triclosan, Amoxicillin and Eugenol against . Int J Clin Pediatr Dent. 2021 Jan-Feb;14(1):59-62. doi: 10.5005/jp-journals-10005-1869. PMID: 34326585; PMCID: PMC8311773.
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Int J Clin Pediatr Dent. 2021 Jan-Feb;14(1):59-62. doi: 10.5005/jp-journals-10005-1869.

Comparative Assessment of the Antimicrobial Efficacy of Triclosan, Amoxicillin and Eugenol against .

International journal of clinical pediatric dentistry

Jagadish Gowda, Ananda Tavarageri, Raghavendra Kulkarni, Rajesh T Anegundi, Apoorva Janardhan, Manohara A Bhat

Affiliations

  1. Department of Paediatric Dentistry, Farooqia Dental College, Mysore, Karnataka, India.
  2. Department of Paediatric Dentistry, SDM College of Dental Sciences, Dharwad, Karnataka, India.
  3. Department of Microbiology, SDM College of Medical Sciences, Dharwad, Karnataka, India.
  4. Department of Conservative Dentistry, JSS Dental College, Mysore, Karnataka, India.
  5. Department of Dentistry, Mysore Medical College and Research Institute, Mysore, Karnataka, India.

PMID: 34326585 PMCID: PMC8311773 DOI: 10.5005/jp-journals-10005-1869

Abstract

AIMS: Elimination of microorganisms and prevention of recurrence of infection from the complex root canal system of primary teeth requires an obturating material with broad antimicrobial activity. Hence, the purpose of the study is to assess and compare the antimicrobial efficacy of Triclosan, Amoxicillin and Eugenol individually and in combinations against a resistant microorganism viz.,

MATERIALS AND METHODS: A two-fold serial dilution method was used to check the minimum inhibitory concentration (MIC) of triclosan, amoxicillin and eugenol against thirty

RESULTS: The mean MIC and MBC of triclosan was 3.43 μg/mL and 3.75 μg/mL respectively. Whereas for amoxicillin, it was 3.43 μg/mL and 3.85 μg/mL. Eugenol did not show any inhibition up to a concentration of 3200 μg/mL. In combination, eugenol showed good synergistic effect with both triclosan and amoxicillin. In combination with triclosan, eugenol showed much promising result as compared with amoxicillin. But triclosan and amoxicillin combination showed inhibition at higher concentrations.

CONCLUSION: Triclosan and eugenol combination showed better effectiveness against

HOW TO CITE THIS ARTICLE: Gowda J, Tavarageri A, Kulkarni R,

Copyright © 2021; Jaypee Brothers Medical Publishers (P) Ltd.

Keywords: Amoxicillin; Double dilution method; Eugenol; Modified checkerboard method; Triclosan

Conflict of interest statement

Source of support: Nil Conflict of interest: None

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