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d'Uscio LV, Katusic ZS. Endothelium-specific deletion of amyloid-β precursor protein exacerbates endothelial dysfunction induced by aging. Aging (Albany NY). 2021;13(15):19165-19185doi: 10.18632/aging.203401.
d'Uscio, L. V., & Katusic, Z. S. (2021). Endothelium-specific deletion of amyloid-β precursor protein exacerbates endothelial dysfunction induced by aging. Aging, 13(15), 19165-19185. https://doi.org/10.18632/aging.203401
d'Uscio, Livius V, and Katusic, Zvonimir S. "Endothelium-specific deletion of amyloid-β precursor protein exacerbates endothelial dysfunction induced by aging." Aging vol. 13,15 (2021): 19165-19185. doi: https://doi.org/10.18632/aging.203401
d'Uscio LV, Katusic ZS. Endothelium-specific deletion of amyloid-β precursor protein exacerbates endothelial dysfunction induced by aging. Aging (Albany NY). 2021 Aug 12;13(15):19165-19185. doi: 10.18632/aging.203401. Epub 2021 Aug 12. PMID: 34382945; PMCID: PMC8386539.
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Aging (Albany NY). 2021 Aug 12;13(15):19165-19185. doi: 10.18632/aging.203401. Epub 2021 Aug 12.

Endothelium-specific deletion of amyloid-β precursor protein exacerbates endothelial dysfunction induced by aging.

Aging

Livius V d'Uscio, Zvonimir S Katusic

Affiliations

  1. Departments of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, MN 55902, USA.

PMID: 34382945 PMCID: PMC8386539 DOI: 10.18632/aging.203401

Abstract

The physiological function of amyloid precursor protein (APP) in the control of endothelial function during aging is unclear. Aortas of young (4-6 months old) and aged (23-26 months old) wild-type (WT) and endothelium-specific APP-deficient (eAPP

Keywords: aging; amyloid precursor protein; endothelial nitric oxide synthase; endothelium; prostaglandins

References

  1. J Neurosci. 2009 Nov 18;29(46):14451-62 - PubMed
  2. Development. 2014 Jul;141(13):2543-8 - PubMed
  3. J Alzheimers Dis. 2015;50(3):817-26 - PubMed
  4. Am J Physiol Heart Circ Physiol. 2011 Sep;301(3):H1025-32 - PubMed
  5. Brain Res Mol Brain Res. 1992 Nov;16(1-2):128-34 - PubMed
  6. Circulation. 2003 Jan 7;107(1):139-46 - PubMed
  7. Proc Natl Acad Sci U S A. 1992 Jul 1;89(13):6075-9 - PubMed
  8. Circ Res. 2010 Dec 10;107(12):1498-502 - PubMed
  9. Hypertension. 1991 Nov;18(5 Suppl):III86-92 - PubMed
  10. FASEB J. 2003 Jun;17(9):1183-5 - PubMed
  11. Cardiovasc Res. 2012 Dec 1;96(3):504-12 - PubMed
  12. Circulation. 2002 Sep 10;106(11):1349-54 - PubMed
  13. Aging (Albany NY). 2017 Jun 28;9(6):1595-1606 - PubMed
  14. Circulation. 2003 Nov 11;108(19):2317-22 - PubMed
  15. J Biol Chem. 2010 Dec 17;285(51):40097-103 - PubMed
  16. Exp Gerontol. 2004 May;39(5):687-99 - PubMed
  17. Am J Physiol Heart Circ Physiol. 2014 Apr 1;306(7):H1001-10 - PubMed
  18. Nature. 1987 Feb 19-25;325(6106):733-6 - PubMed
  19. Kidney Int. 2007 Nov;72(9):1073-80 - PubMed
  20. J Aging Res. 2012;2012:121390 - PubMed
  21. Proc Natl Acad Sci U S A. 2005 Apr 19;102(16):5727-32 - PubMed
  22. Circ Res. 2005 Feb 4;96(2):164-71 - PubMed
  23. Proc Natl Acad Sci U S A. 1988 Oct;85(19):7341-5 - PubMed
  24. Front Physiol. 2016 Sep 07;7:386 - PubMed
  25. Proc Natl Acad Sci U S A. 1991 Dec 1;88(23):10480-4 - PubMed
  26. J Gerontol A Biol Sci Med Sci. 2009 Jan;64(1):9-20 - PubMed
  27. Proc Natl Acad Sci U S A. 1999 Mar 30;96(7):3922-7 - PubMed
  28. Nature. 1988 Feb 11;331(6156):528-30 - PubMed
  29. Hypertension. 2006 Aug;48(2):323-8 - PubMed
  30. Hypertension. 1997 Mar;29(3):736-43 - PubMed
  31. Acta Pharmacol Sin. 2010 Sep;31(9):1095-102 - PubMed
  32. Am J Physiol Renal Physiol. 2010 Sep;299(3):F656-63 - PubMed
  33. Physiology (Bethesda). 2017 Jan;32(1):20-32 - PubMed
  34. Antioxid Redox Signal. 2001 Apr;3(2):203-13 - PubMed
  35. Hypertension. 1990 May;15(5):475-81 - PubMed
  36. J Biol Chem. 2012 Nov 23;287(48):40817-25 - PubMed
  37. J Cereb Blood Flow Metab. 2018 Oct;38(10):1715-1726 - PubMed
  38. Nature. 1988 Jun 16;333(6174):664-6 - PubMed
  39. PLoS One. 2017 Nov 2;12(11):e0187189 - PubMed
  40. J Clin Invest. 1993 Aug;92(2):652-62 - PubMed
  41. Stroke. 2012 Dec;43(12):3358-63 - PubMed
  42. Atherosclerosis. 2009 Oct;206(2):397-404 - PubMed
  43. J Cereb Blood Flow Metab. 2020 Feb;40(2):392-403 - PubMed
  44. Am J Physiol Regul Integr Comp Physiol. 2004 Jul;287(1):R27-32 - PubMed
  45. Arterioscler Thromb Vasc Biol. 2001 Jun;21(6):1017-22 - PubMed
  46. Circulation. 2004 Nov 2;110(18):2889-95 - PubMed
  47. Clin Exp Pharmacol Physiol. 2010 Apr;37(4):429-34 - PubMed
  48. Science. 1990 May 11;248(4956):745-8 - PubMed
  49. Hypertension. 1996 Dec;28(6):1064-9 - PubMed
  50. Prostaglandins Leukot Essent Fatty Acids. 2013 Aug;89(2-3):55-63 - PubMed
  51. Neuron. 1990 Feb;4(2):253-67 - PubMed
  52. Nature. 1992 Jun 11;357(6378):500-3 - PubMed
  53. Cell Rep. 2020 Mar 31;30(13):4418-4432.e4 - PubMed
  54. Am J Physiol Heart Circ Physiol. 2011 Dec;301(6):H2227-34 - PubMed
  55. Brain Res. 2016 Oct 1;1648(Pt B):588-593 - PubMed
  56. J Cereb Blood Flow Metab. 2017 Jan;37(1):106-122 - PubMed
  57. Int J Cardiol. 2014 Aug 20;175(3):446-50 - PubMed
  58. Physiol Genomics. 2008 Feb 19;32(3):409-18 - PubMed
  59. Am J Physiol. 1997 Sep;273(3 Pt 2):H1478-83 - PubMed
  60. Proc Natl Acad Sci U S A. 1989 Oct;86(19):7606-10 - PubMed
  61. Hypertension. 1995 Feb;25(2):194-200 - PubMed
  62. Circ Res. 2009 Jan 30;104(2):228-35 - PubMed
  63. Circulation. 2013 Mar 26;127(12):1308-16 - PubMed
  64. Arterioscler Thromb Vasc Biol. 2007 Sep;27(9):1941-6 - PubMed
  65. J Am Coll Cardiol. 1994 Aug;24(2):471-6 - PubMed
  66. Hypertension. 2017 Sep;70(3):613-623 - PubMed
  67. Nature. 1995 Sep 21;377(6546):239-42 - PubMed

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