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Euro Surveill. 2021 Aug;26(31). doi: 10.2807/1560-7917.ES.2021.26.31.2100640.

Vaccine effectiveness against SARS-CoV-2 transmission and infections among household and other close contacts of confirmed cases, the Netherlands, February to May 2021.

Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin

Brechje de Gier, Stijn Andeweg, Rosa Joosten, Ronald Ter Schegget, Naomi Smorenburg, Jan van de Kassteele, Susan Jm Hahné, Susan van den Hof, Hester E de Melker, Mirjam J Knol,

Affiliations

  1. Center for Infectious Disease Control, National Institute for Public Health and the Environment (RIVM), Bilthoven, the Netherlands.
  2. GGD Brabant Zuidoost, Eindhoven, the Netherlands.

PMID: 34355689 PMCID: PMC8343550 DOI: 10.2807/1560-7917.ES.2021.26.31.2100640

Abstract

Several studies report high effectiveness of COVID-19 vaccines against SARS-CoV-2 infection and severe disease, however an important knowledge gap is the vaccine effectiveness against transmission (VET). We present estimates of the VET to household and other close contacts in the Netherlands, from February to May 2021, using contact monitoring data. The secondary attack rate among household contacts was lower for fully vaccinated than unvaccinated index cases (11% vs 31%), with an adjusted VET of 71% (95% confidence interval: 63-77).

Keywords: COVID-19; SARS-CoV-2; household study; transmission; vaccine effectiveness

References

  1. Vaccine. 2012 Apr 19;30(19):2999-3002 - PubMed
  2. Euro Surveill. 2020 Dec;25(50): - PubMed
  3. Am J Epidemiol. 1991 Feb 15;133(4):323-31 - PubMed
  4. Euro Surveill. 2021 May;26(21): - PubMed
  5. N Engl J Med. 2021 Aug 19;385(8):759-760 - PubMed

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