Display options
Cite
Reasoner SA, Enriquez KT, Abelson B, et al. Urinary tract infections in cystic fibrosis patients. J Cyst Fibros. 2021;doi: 10.1016/j.jcf.2021.07.005.
Reasoner, S. A., Enriquez, K. T., Abelson, B., Scaglione, S., Schneier, B., O'Connor, M. G., Van Horn, G., & Hadjifrangiskou, M. (2021). Urinary tract infections in cystic fibrosis patients. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, . https://doi.org/10.1016/j.jcf.2021.07.005
Reasoner, Seth A, et al. "Urinary tract infections in cystic fibrosis patients." Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society vol. (2021). doi: https://doi.org/10.1016/j.jcf.2021.07.005
Reasoner SA, Enriquez KT, Abelson B, Scaglione S, Schneier B, O'Connor MG, Van Horn G, Hadjifrangiskou M. Urinary tract infections in cystic fibrosis patients. J Cyst Fibros. 2021 Jul 27; doi: 10.1016/j.jcf.2021.07.005. Epub 2021 Jul 27. PMID: 34330649.
Copy Download .nbib Format: NLM
Share it on

J Cyst Fibros. 2021 Jul 27; doi: 10.1016/j.jcf.2021.07.005. Epub 2021 Jul 27.

Urinary tract infections in cystic fibrosis patients.

Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society

Seth A Reasoner, Kyle T Enriquez, Benjamin Abelson, Steven Scaglione, Bennett Schneier, Michael G O'Connor, Gerald Van Horn, Maria Hadjifrangiskou

Affiliations

  1. Division of Molecular Pathogenesis, Department of Pathology, Microbiology & Immunology, Vanderbilt University Medical Center, Nashville, TN, United States.
  2. Vanderbilt University School of Medicine, Nashville, TN, United States.
  3. Division of Pediatric Urology, Department of Urology, Vanderbilt University Medical Center, Nashville, TN, United States.
  4. Division of Pediatric Pulmonary, Allergy, and Immunology, Department of Pediatrics, Vanderbilt University Medical Center, Nashville, TN, United States.
  5. Division of Molecular Pathogenesis, Department of Pathology, Microbiology & Immunology, Vanderbilt University Medical Center, Nashville, TN, United States; Center for Personalized Microbiology (CPMi), Vanderbilt University Medical Center, Nashville, TN.
  6. Division of Molecular Pathogenesis, Department of Pathology, Microbiology & Immunology, Vanderbilt University Medical Center, Nashville, TN, United States; Center for Personalized Microbiology (CPMi), Vanderbilt University Medical Center, Nashville, TN; Vanderbilt Institute for Infection, Immunology & Inflammation (VI4), Vanderbilt University Medical Center, Nashville, TN, United States. Electronic address: [email protected].

PMID: 34330649 DOI: 10.1016/j.jcf.2021.07.005

Abstract

Improved understanding of non-respiratory infections in cystic fibrosis (CF) patients will be vital to sustaining the increased life span of these patients. To date, there has not been a published report of urinary tract infections (UTIs) in CF patients. We performed a retrospective chart review at a major academic medical center during 2010-2020 to determine the features of UTIs in 826 CF patients. We identified 108 UTI episodes during this period. Diabetes, distal intestinal obstruction syndrome (DIOS), and nephrolithiasis were correlated with increased risk of UTIs. UTIs in CF patients were less likely to be caused by Gram-negative rods compared to non-CF patients and more likely to be caused by Enterococcus faecalis. The unique features of UTIs in CF patients highlight the importance of investigating non-respiratory infections to ensure appropriate treatment.

Copyright © 2021. Published by Elsevier B.V.

Keywords: Antibiotic resistance; Cystic fibrosis; Cystitis; Urinary tract infection

Conflict of interest statement

Declaration of Competing Interest All authors declare that they have no conflicts of interest.

Publication Types