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J Pediatr Hematol Oncol. 2021 Aug 16; doi: 10.1097/MPH.0000000000002279. Epub 2021 Aug 16.

Juvenile Xanthogranuloma of the Pancreas in a Pediatric Patient Mimicking Pancreatic Neoplasm With High CA 19-9: Case Report and Literature Review.

Journal of pediatric hematology/oncology

Eman Al-Antary, Avanti Gupte, Janet Poulik, Justin Klein, Hamza S Gorsi

Affiliations

  1. Pediatric Hematology/Oncology and Bone Marrow Transplantation Program Pediatric Pathology Department Pediatric General Surgery Program, Children's Hospital of Michigan, Central Michigan University and Wayne State University School of Medicine, Detroit, MI.

PMID: 34387630 DOI: 10.1097/MPH.0000000000002279

Abstract

Juvenile xanthogranuloma (JXG) is a rare, non-Langerhans cell histiocytosis. It is usually a benign and self-limiting condition. The most common sites are skin and soft tissue. Pancreatic involvement is extremely rare. We present an unusual case of a 13-month-old female child with JXG of the pancreas and elevated cancer antigen 19-9. JXG should always be considered as a differential diagnosis for pediatric patients presenting with a pancreatic mass, solid and/or cystic in nature. Therefore, avoiding unnecessary invasive diagnostic procedures.

Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.

Conflict of interest statement

The authors declare no conflict of interest.

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