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Brennan R, Wazaify M, Shawabkeh H, et al. A Scoping Review of Non-Medical and Extra-Medical Use of Non-Steroidal Anti-Inflammatory Drugs (NSAIDs). Drug Saf. 2021;44(9):917-928doi: 10.1007/s40264-021-01085-9.
Brennan, R., Wazaify, M., Shawabkeh, H., Boardley, I., McVeigh, J., & Van Hout, M. C. (2021). A Scoping Review of Non-Medical and Extra-Medical Use of Non-Steroidal Anti-Inflammatory Drugs (NSAIDs). Drug safety, 44(9), 917-928. https://doi.org/10.1007/s40264-021-01085-9
Brennan, Rebekah, et al. "A Scoping Review of Non-Medical and Extra-Medical Use of Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)." Drug safety vol. 44,9 (2021): 917-928. doi: https://doi.org/10.1007/s40264-021-01085-9
Brennan R, Wazaify M, Shawabkeh H, Boardley I, McVeigh J, Van Hout MC. A Scoping Review of Non-Medical and Extra-Medical Use of Non-Steroidal Anti-Inflammatory Drugs (NSAIDs). Drug Saf. 2021 Sep;44(9):917-928. doi: 10.1007/s40264-021-01085-9. Epub 2021 Jul 30. PMID: 34331260; PMCID: PMC8370940.
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Drug Saf. 2021 Sep;44(9):917-928. doi: 10.1007/s40264-021-01085-9. Epub 2021 Jul 30.

A Scoping Review of Non-Medical and Extra-Medical Use of Non-Steroidal Anti-Inflammatory Drugs (NSAIDs).

Drug safety

Rebekah Brennan, Mayyada Wazaify, Haneen Shawabkeh, Ian Boardley, Jim McVeigh, Marie Claire Van Hout

Affiliations

  1. School of Applied Social Studies, University College Cork, Cork, Ireland. [email protected].
  2. Department of Biopharmaceutics and Clinical Pharmacy, School of Pharmacy, The University of Jordan, Amman, Jordan.
  3. School of Sport, Exercise and Rehabilitation Sciences, University of Birmingham, Edgbaston, Birmingham, UK.
  4. Substance Use & Associated Behaviours, Department of Sociology, Manchester Metropolitan University, Manchester, UK.
  5. Faculty of Health, Public Health Institute, Liverpool John Moore's University, Liverpool, UK.

PMID: 34331260 PMCID: PMC8370940 DOI: 10.1007/s40264-021-01085-9

Abstract

Non-steroidal anti-inflammatory drugs (NSAIDs) are among the most commonly used medications worldwide and have analgesic, antipyretic and anti-inflammatory properties. Although NSAIDs are recognised as generally safe and effective, non-medical and extra-medical use of these products can occur. Unlike the use of illegal and many prescription drugs, which are subject to extensive research attention, inappropriate use of NSAIDs has been less well investigated. This scoping review collates and describes what is known regarding non-medical and extra-medical use of NSAIDs. In total, 72 studies were included in this scoping review. Three themes emerged from the review: (1) indicative profile of people who engage in non-medical or extra-medical use of NSAIDs; (2) antecedents for non-medical or extra-medical use; and (3) adverse health effects of non-medical and extra-medical use of NSAIDs. The review concluded that there is a need for enhanced patient education, including among sports people; pharmacovigilance in terms of clinician recognition of aberrance; and prescriber and pharmacist awareness of the potential for extra-medical and non-medical use and the related health harms.

© 2021. The Author(s).

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