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Ramos-Languren LE, Avila-Luna A, García-Díaz G, et al. Glutamate, Glutamine, GABA and Oxidative Products in the Pons Following Cortical Injury and Their Role in Motor Functional Recovery. Neurochem Res. 2021;46(12):3179-3189doi: 10.1007/s11064-021-03417-8.
Ramos-Languren, L. E., Avila-Luna, A., García-Díaz, G., Rodríguez-Labrada, R., Vázquez-Mojena, Y., Parra-Cid, C., Montes, S., Bueno-Nava, A., & González-Piña, R. (2021). Glutamate, Glutamine, GABA and Oxidative Products in the Pons Following Cortical Injury and Their Role in Motor Functional Recovery. Neurochemical research, 46(12), 3179-3189. https://doi.org/10.1007/s11064-021-03417-8
Ramos-Languren, Laura E, et al. "Glutamate, Glutamine, GABA and Oxidative Products in the Pons Following Cortical Injury and Their Role in Motor Functional Recovery." Neurochemical research vol. 46,12 (2021): 3179-3189. doi: https://doi.org/10.1007/s11064-021-03417-8
Ramos-Languren LE, Avila-Luna A, García-Díaz G, Rodríguez-Labrada R, Vázquez-Mojena Y, Parra-Cid C, Montes S, Bueno-Nava A, González-Piña R. Glutamate, Glutamine, GABA and Oxidative Products in the Pons Following Cortical Injury and Their Role in Motor Functional Recovery. Neurochem Res. 2021 Dec;46(12):3179-3189. doi: 10.1007/s11064-021-03417-8. Epub 2021 Aug 13. PMID: 34387812.
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Neurochem Res. 2021 Dec;46(12):3179-3189. doi: 10.1007/s11064-021-03417-8. Epub 2021 Aug 13.

Glutamate, Glutamine, GABA and Oxidative Products in the Pons Following Cortical Injury and Their Role in Motor Functional Recovery.

Neurochemical research

Laura E Ramos-Languren, Alberto Avila-Luna, Gabriela García-Díaz, Roberto Rodríguez-Labrada, Yaimee Vázquez-Mojena, Carmen Parra-Cid, Sergio Montes, Antonio Bueno-Nava, Rigoberto González-Piña

Affiliations

  1. Faculty of Psychology, Coordination of Psychobiology and Neurosciences, National Autonomous University of Mexico, Av. Universidad 3040 Col, Copilco Universidad Alcaldía Coyoacán, 04510, Mexico City, Mexico.
  2. National Institute of Rehabilitation LGII, Calz. Mexico-Xochimilco #289 Col. Arenal de Guadalupe Alcaldía Tlalpan, 14389, Mexico City, Mexico.
  3. Section of Postgraduate Studies and Research, High Medical School, IPN. Salvador Diaz Miron Alcaldia Miguel Hidalgo, 11340, Mexico City, Mexico.
  4. School of Physical Culture, University of Holguín, Avenida XX Aniversario, 80100, Holguín, Cuba.
  5. Cuban Centre for Neurosciences, Calle 190 entre 25 y 27, Playa, 11300, Havana City, Cuba.
  6. Reynosa-Aztlan Multidisciplinary Unit, Autonomous University of Tamaulipas, Fuente de Diana, Aztlán, 88740, Tamaulipas, Mexico.
  7. Laboratory of Aging Biology, National Geriatric Institute, Av. Contreras 428 Col. San Jerónimo Lídice Alcaldía Magdalena Contreras, 10200, Mexico City, Mexico. [email protected].
  8. Section of Postgraduate Studies and Research, High Medical School, IPN. Salvador Diaz Miron Alcaldia Miguel Hidalgo, 11340, Mexico City, Mexico. [email protected].
  9. Department of Special Education, University of the Americas Mexico City College, Puebla # 223 Col. Roma Alcaldía Cuauhtemoc, 06700, Mexico City, Mexico. [email protected].

PMID: 34387812 DOI: 10.1007/s11064-021-03417-8

Abstract

Brain injury leads to an excitatory phase followed by an inhibitory phase in the brain. The clinical sequelae caused by cerebral injury seem to be a response to remote functional inhibition of cerebral nuclei located far from the motor cortex but anatomically related to the injury site. It appears that such functional inhibition is mediated by an increase in lipid peroxidation (LP). To test this hypothesis, we report data from 80 rats that were allocated to the following groups: the sham group (n = 40), in which rats received an intracortical infusion of artificial cerebrospinal fluid (CSF); the injury group (n = 20), in which rats received CSF containing ferrous chloride (FeCl

© 2021. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

Keywords: Brain injury; Cerebellum; Lipid peroxidation; Pons; Rats

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