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Fesas A, Giannoula E, Vrachimis A, et al. Cardiac Autonomic Nervous System and Ventricular Arrhythmias: The Role of Radionuclide Molecular Imaging. Diagnostics (Basel). 2021;11(7)doi: 10.3390/diagnostics11071273.
Fesas, A., Giannoula, E., Vrachimis, A., Doumas, A., Wenning, C., Didagelos, M., & Iakovou, I. (2021). Cardiac Autonomic Nervous System and Ventricular Arrhythmias: The Role of Radionuclide Molecular Imaging. Diagnostics (Basel, Switzerland), 11(7), . https://doi.org/10.3390/diagnostics11071273
Fesas, Andreas, et al. "Cardiac Autonomic Nervous System and Ventricular Arrhythmias: The Role of Radionuclide Molecular Imaging." Diagnostics (Basel, Switzerland) vol. 11,7 (2021). doi: https://doi.org/10.3390/diagnostics11071273
Fesas A, Giannoula E, Vrachimis A, Doumas A, Wenning C, Didagelos M, Iakovou I. Cardiac Autonomic Nervous System and Ventricular Arrhythmias: The Role of Radionuclide Molecular Imaging. Diagnostics (Basel). 2021 Jul 15;11(7). doi: 10.3390/diagnostics11071273. PMID: 34359356; PMCID: PMC8303842.
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Diagnostics (Basel). 2021 Jul 15;11(7). doi: 10.3390/diagnostics11071273.

Cardiac Autonomic Nervous System and Ventricular Arrhythmias: The Role of Radionuclide Molecular Imaging.

Diagnostics (Basel, Switzerland)

Andreas Fesas, Evanthia Giannoula, Alexis Vrachimis, Argyrios Doumas, Christian Wenning, Matthaios Didagelos, Ioannis Iakovou

Affiliations

  1. Department of Nuclear Medicine, German Oncology Center, University Hospital of the European University, 4108 Limassol, Cyprus.
  2. Second Academic Nuclear Medicine Department of Aristotle University, AHEPA Acad. Hospital, 54636 Thessaloniki, Greece.
  3. C.A.R.I.C. Cancer Research & Innovation Center, 4108 Limassol, Cyprus.
  4. Department of Nuclear Medicine, Bonifatius Hospital gGmbH, 49808 Lingen, Germany.
  5. 1st Cardiology Department, of Aristotle University, AHEPA Acad. Hospital, 54636 Thessaloniki, Greece.

PMID: 34359356 PMCID: PMC8303842 DOI: 10.3390/diagnostics11071273

Abstract

Widely established compared to myocardial perfusion imaging, cardiac autonomous nervous system (CANS) assessment by radiopharmaceutical means is of potential use especially to arrhythmogenic diseases not correlated with anatomic or functional alterations revealed by classical imaging techniques. Molecular imaging of both pre- and postsynaptic functions of the autonomous nervous system is currently feasible, since single photon emission tomography (SPECT) and positron emission tomography (PET) have the ability to reveal the insights of molecular pathophysiology depicting both sympathetic and parasympathetic imbalance in discrete heart pathologies. This review provides not only a brief presentation of radiopharmaceuticals used for non-invasive CANS imaging in the case of ventricular arrhythmias, but also a current update on ventricular tachycardias, cardiomyopathies, Brugada and Long QT syndrome literature.

Keywords: PET 1; SPECT 2; arrhythmias 3; autonomous nervous system imaging 4; radiopharmaceuticals 5

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