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Food Chem Toxicol. 2021 Oct;156:112524. doi: 10.1016/j.fct.2021.112524. Epub 2021 Aug 26.

Latest advances on the nanomaterials-based electrochemical analysis of azo toxic dyes Sunset Yellow and Tartrazine in food samples.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association

S Irem Kaya, Ahmet Cetinkaya, Sibel A Ozkan

Affiliations

  1. Ankara University, Faculty of Pharmacy, Department of Analytical Chemistry, 06560, Ankara, Turkey; University of Health Sciences, Gulhane Faculty of Pharmacy, Department of Analytical Chemistry, Ankara, Turkey.
  2. Ankara University, Faculty of Pharmacy, Department of Analytical Chemistry, 06560, Ankara, Turkey.
  3. Ankara University, Faculty of Pharmacy, Department of Analytical Chemistry, 06560, Ankara, Turkey. Electronic address: [email protected].

PMID: 34454997 DOI: 10.1016/j.fct.2021.112524

Abstract

Azo-dyes such as Allura Red, Carmoisine, Amaranth, Sunset Yellow (SY), Brilliant Blue, Tartrazine (Tz), etc., are popular as food coloring agents due to their low cost and stability. SY and Tz are the most used members of this group of dyes since they have similar colors and are usually used together in food products. Despite their advantageous industrial use, they exhibit a risk toxicity profile with adverse effects such as allergy, asthma, carcinogenicity, genotoxicity, cytotoxicity, anxiety, etc. Therefore, the United States Food and Drug Administration (FDA) and European Food Safety Authority (EFSA) regulate the permissions for using these compounds to provide safe food products for consumers and prevent adverse effects both short and long-term. Considering all of these, for the analysis of azo toxic dyes, highly sensitive, low-cost, simple, and rapid sensors are necessary. Electrochemical nanosensors, which combine the unique features of electrochemistry and nanotechnology, are devices with all these advantages and are widely used for the determination of azo dyes. SY and Tz step forth as the most used food dyes in the class of azo-toxic dyes. They are often preferred together in food products, increasing the occurrence and exposure risk. Therefore, the analysis of Sunset Yellow and Tartrazine in food products has significant importance. In this review, the latest nanomaterial-based approaches for the electrochemical sensors on the analysis of SY and Tz in food samples were evaluated in terms of used nanomaterials and applied food samples.

Copyright © 2021 Elsevier Ltd. All rights reserved.

Keywords: Electrochemistry; Food analysis; Nanosensor; Sunset yellow; Tartrazine

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