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Laurent S, Chatellier G, Azizi M, et al. SPARTE Study: Normalization of Arterial Stiffness and Cardiovascular Events in Patients With Hypertension at Medium to Very High Risk. Hypertension. 2021;78(4):983-995doi: 10.1161/HYPERTENSIONAHA.121.17579.
Laurent, S., Chatellier, G., Azizi, M., Calvet, D., Choukroun, G., Danchin, N., Delsart, P., Girerd, X., Gosse, P., Khettab, H., London, G., Mourad, J. J., Pannier, B., Pereira, H., Stephan, D., Valensi, P., Cunha, P., Narkiewicz, K., Bruno, R. M., Boutouyrie, P. (2021). SPARTE Study: Normalization of Arterial Stiffness and Cardiovascular Events in Patients With Hypertension at Medium to Very High Risk. Hypertension (Dallas, Tex. : 1979), 78(4), 983-995. https://doi.org/10.1161/HYPERTENSIONAHA.121.17579
Laurent, Stephane, et al. "SPARTE Study: Normalization of Arterial Stiffness and Cardiovascular Events in Patients With Hypertension at Medium to Very High Risk." Hypertension (Dallas, Tex. : 1979) vol. 78,4 (2021): 983-995. doi: https://doi.org/10.1161/HYPERTENSIONAHA.121.17579
Laurent S, Chatellier G, Azizi M, Calvet D, Choukroun G, Danchin N, Delsart P, Girerd X, Gosse P, Khettab H, London G, Mourad JJ, Pannier B, Pereira H, Stephan D, Valensi P, Cunha P, Narkiewicz K, Bruno RM, Boutouyrie P. SPARTE Study: Normalization of Arterial Stiffness and Cardiovascular Events in Patients With Hypertension at Medium to Very High Risk. Hypertension. 2021 Sep;78(4):983-995. doi: 10.1161/HYPERTENSIONAHA.121.17579. Epub 2021 Aug 30. PMID: 34455813; PMCID: PMC8415523.
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Hypertension. 2021 Sep;78(4):983-995. doi: 10.1161/HYPERTENSIONAHA.121.17579. Epub 2021 Aug 30.

SPARTE Study: Normalization of Arterial Stiffness and Cardiovascular Events in Patients With Hypertension at Medium to Very High Risk.

Hypertension (Dallas, Tex. : 1979)

Stephane Laurent, Gilles Chatellier, Michel Azizi, David Calvet, Gabriel Choukroun, Nicolas Danchin, Pascal Delsart, Xavier Girerd, Philippe Gosse, Hakim Khettab, Gerard London, Jean-Jacques Mourad, Bruno Pannier, Helena Pereira, Dominique Stephan, Paul Valensi, Pedro Cunha, Krzysztof Narkiewicz, Rosa-Maria Bruno, Pierre Boutouyrie,

Affiliations

  1. From the Université de Paris, France (S.L., G. Chatellier, M.A., N.D., R.-M.B., P.B.).
  2. Assistance-Publique Hopitaux de Paris, Georges Pompidou European Hospital, Paris, France (S.L., G. Chatellier, M.A., N.D., H.K., R.-M.B., P.B.).
  3. Clinical Research Unit, INSERM U970, Paris (G. Chatellier, H.P.).
  4. Hypertension Department and DMU CARTE, Paris, France (M.A.).
  5. INSERM, CIC1418, Paris, France (M.A.).
  6. Neurology department, GHU Paris Psychiatrie Neurosciences, Sainte-Anne Hospital (D.C.).
  7. INSERM UMR 1266, FHU NeuroVasc, Paris, France (D.C.).
  8. Nephrology Dialysis Transplantation Department, CHU Amiens, France (G. Choukroun).
  9. MP3CV Research Unit, University Picardie Jules Verne, France (G. Choukroun).
  10. Cardiology Department, Georges Pompidou Hospital, Paris, France (N.D.).
  11. CHU Lille, Institut Cœur Poumon, Lille, France (P.D.).
  12. ICAN, Sorbonne University, Assistance-Publique Hopitaux de Paris, Paris, France (X.G.).
  13. Cardiology Department, Saint Andre Hospital, CHU Bordeaux, France (P.G.).
  14. INSERM U970, Cardiovascular Research Center - PARCC, Paris, France (H.K., R.-M.B., P.B.).
  15. Department of Nephrology, Manhes Hospital, Fleury Merogis, France(G.L.).
  16. Paris Saint-Joseph Hospital, Paris, France (J.-J.M.).
  17. Department of Internal Medicine, Manhes Hospital, Fleury Merogis, France (B.P.).
  18. University of Strasbourg, France (D.S.).
  19. UMR 1260, INSERM-University of Strasbourg, France (D.S.).
  20. Unit of Endocrinology-Diabetology-Nutrition, Assistance-Publique Hopitaux de Paris, Jean Verdier Hospital, University Sorbonne Paris Cite, Bondy, France (P.V.).
  21. Center for the Research and Treatment of Arterial Hypertension and Cardiovascular Risk, Internal Medicine Department, Guimaraes, Portugal (P.C.).
  22. Life and Health Research Institute (ICVS/3B's), Minho University, Portugal (P.C.).
  23. Department of Hypertension and Diabetology, Faculty of Medicine, Medical University of Gdansk, Debinki, Gdansk, Poland (K.N.).

PMID: 34455813 PMCID: PMC8415523 DOI: 10.1161/HYPERTENSIONAHA.121.17579

Abstract

[Figure: see text].

Keywords: blood pressure; clinical trial; hypertension; renin-angiotensin system; surrogate end point; vascular stiffness

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