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J Appl Physiol (1985). 2021 Nov 01;131(5):1432-1443. doi: 10.1152/japplphysiol.00363.2021. Epub 2021 Aug 26.

Severity of central sleep apnea does not affect sleeping oxygen saturation during ascent to high altitude.

Journal of applied physiology (Bethesda, Md. : 1985)

Jordan D Bird, Anne Kalker, Alexander N Rimke, Jason S Chan, Garrick Chan, Gurkarn Saran, Nicholas G Jendzjowsky, Richard J A Wilson, Thomas D Brutsaert, Mingma T Sherpa, Trevor A Day

Affiliations

  1. Faculty of Science and Technology, Department of Biology, Mount Royal University, Calgary, Alberta, Canada.
  2. Radboud University Medical Center, Nijmegen, The Netherlands.
  3. Respiratory Medicine and Exercise Physiology, The Lundquist Institute for Biomedical Innovation, Harbor UCLA Medical Center, West Carson, California.
  4. Department of Physiology and Pharmacology, Hotchkiss Brain Institute and Alberta Children's Hospital Research Institute, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
  5. Department of Exercise Science, School of Education, Syracuse University, Syracuse, New York.
  6. Kunde Hospital, Khunde, Nepal.

PMID: 34435507 DOI: 10.1152/japplphysiol.00363.2021

Abstract

Central sleep apnea (CSA) is characterized by periodic breathing (PB) during sleep, defined as intermittent periods of apnea/hypopnea and hyperventilation, with associated acute fluctuations in oxyhemoglobin saturation (SO

Keywords: central sleep apnea; high-altitude ascent; oxygen saturation; periodic breathing; respiratory chemoreflexes

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