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Postepy Dermatol Alergol. 2021 Apr;38(2):262-268. doi: 10.5114/ada.2021.106202. Epub 2021 May 22.

Relationship between CCR5.

Postepy dermatologii i alergologii

Łukasz Kraszula, Makandjou-Ola Eusebio, Piotr Kuna, Mirosława Pietruczuk

Affiliations

  1. Department of Laboratory Diagnostics, Second Chair of Internal Medicine, Medical University of Lodz, Lodz, Poland.
  2. Department of Internal Medicine, Asthma and Allergy, Second Chair of Internal Medicine, Medical University of Lodz, Lodz, Poland.

PMID: 34408594 PMCID: PMC8362744 DOI: 10.5114/ada.2021.106202

Abstract

INTRODUCTION: Severe asthma is a special clinical problem. CD4

AIM: To evaluate whether CCR5 Tregs expression and surface density on FoxP3

MATERIAL AND METHODS: The study included 50 patients with asthma (25 with severe and 25 with mild-to-moderate asthma). The control group comprised 25 healthy volunteers. The phenotype of CD4

RESULTS: The absolute count of FoxP3

CONCLUSIONS: High CCR5 Tregs expression as MFI is associated with improved in lung function parameters: FEV

Copyright © 2021 Termedia.

Keywords: CCR5; Tregs; asthma

Conflict of interest statement

The authors declare no conflict of interest.

References

  1. Eur Respir J. 2008 Apr;31(4):783-9 - PubMed
  2. Allergy. 2005 Aug;60(8):986-95 - PubMed
  3. J Immunol Res. 2018 Jun 14;2018:3096183 - PubMed
  4. Respir Res. 2018 Jun 8;19(1):113 - PubMed
  5. Eur Respir J. 2003 Sep;22(3):470-7 - PubMed
  6. Pediatr Pulmonol. 2014 Jul;49(7):632-40 - PubMed
  7. Blood. 2005 Nov 1;106(9):3300-7 - PubMed
  8. J Acquir Immune Defic Syndr. 2003 Sep 1;34(1):114-6 - PubMed
  9. Eur J Clin Microbiol Infect Dis. 2015 Feb;34(2):267-75 - PubMed
  10. Trends Immunol. 2003 Mar;24(3):122-6 - PubMed
  11. Allergy Asthma Proc. 2015 Nov-Dec;36(6):418-24 - PubMed
  12. J Immunol Res. 2018 May 29;2018:1292404 - PubMed
  13. Front Immunol. 2018 Jun 21;9:1416 - PubMed
  14. J Allergy Clin Immunol. 2016 Sep;138(3):639-652 - PubMed
  15. PLoS One. 2011;6(9):e24345 - PubMed
  16. Immunol Rev. 2014 May;259(1):231-44 - PubMed
  17. Chest. 2006 Nov;130(5):1454-61 - PubMed
  18. Eur Rev Med Pharmacol Sci. 2016;20(4):698-708 - PubMed
  19. J Allergy Clin Immunol Pract. 2013 Mar;1(2):110-21; quiz 122 - PubMed
  20. J Immunol. 2008 Mar 1;180(5):3049-56 - PubMed
  21. Am J Respir Cell Mol Biol. 2011 Dec;45(6):1248-55 - PubMed
  22. Clin Exp Allergy. 2005 Jan;35(1):26-33 - PubMed
  23. J Asthma. 2019 Mar;56(3):303-310 - PubMed
  24. Proc Natl Acad Sci U S A. 2007 Jan 9;104(2):594-9 - PubMed

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