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Front Microbiol. 2021 Aug 02;12:715863. doi: 10.3389/fmicb.2021.715863. eCollection 2021.

Presence and Germination of the Probiotic .

Frontiers in microbiology

Joan Colom, Daniela Freitas, Annie Simon, Andre Brodkorb, Martin Buckley, John Deaton, Alison M Winger

Affiliations

  1. Deerland Probiotics and Enzymes, Food Science Building, University College Cork, Cork, Ireland.
  2. Teagasc Food Research Centre, Moorepark, Fermoy, Ireland.
  3. Mercy University Hospital, Grenville PI, Cork, Ireland.
  4. Deerland Probiotics and Enzymes, Kennesaw, GA, United States.

PMID: 34408741 PMCID: PMC8366289 DOI: 10.3389/fmicb.2021.715863

Abstract

Spore-based probiotics offer important advantages over other probiotics as they can survive the harsh gastric conditions of the stomach and bile salts in the small intestine, ultimately germinating in the digestive tract. A novel clinical trial in 11 ileostomy participants was conducted to directly investigate the presence and germination of the probiotic strain

Copyright © 2021 Colom, Freitas, Simon, Brodkorb, Buckley, Deaton and Winger.

Keywords: Bacillus subtilis; DE111®; germination; ileostomy; probiotic; small intestine

Conflict of interest statement

JC, AS, JD, and AW are employees of Deerland Probiotics and Enzymes. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that coul

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