Display options
Cite
Delgado-Lezama R, Bravo-Hernández M, Franco-Enzástiga Ú, et al. The role of spinal cord extrasynaptic α. Physiol Rep. 2021;9(16):e14984doi: 10.14814/phy2.14984.
Delgado-Lezama, R., Bravo-Hernández, M., Franco-Enzástiga, �. �., De la Luz-Cuellar, Y. E., Alvarado-Cervantes, N. S., Raya-Tafolla, G., Martínez-Zaldivar, L. A., Vargas-Parada, A., Rodríguez-Palma, E. J., Vidal-Cantú, G. C., Guzmán-Priego, C. G., Torres-López, J. E., Murbartián, J., Felix, R., & Granados-Soto, V. (2021). The role of spinal cord extrasynaptic α. Physiological reports, 9(16), e14984. https://doi.org/10.14814/phy2.14984
Delgado-Lezama, Rodolfo, et al. "The role of spinal cord extrasynaptic α." Physiological reports vol. 9,16 (2021): e14984. doi: https://doi.org/10.14814/phy2.14984
Delgado-Lezama R, Bravo-Hernández M, Franco-Enzástiga Ú, De la Luz-Cuellar YE, Alvarado-Cervantes NS, Raya-Tafolla G, Martínez-Zaldivar LA, Vargas-Parada A, Rodríguez-Palma EJ, Vidal-Cantú GC, Guzmán-Priego CG, Torres-López JE, Murbartián J, Felix R, Granados-Soto V. The role of spinal cord extrasynaptic α. Physiol Rep. 2021 Aug;9(16):e14984. doi: 10.14814/phy2.14984. PMID: 34409771; PMCID: PMC8374381.
Copy Download .nbib Format: NLM
Share it on

Physiol Rep. 2021 Aug;9(16):e14984. doi: 10.14814/phy2.14984.

The role of spinal cord extrasynaptic α.

Physiological reports

Rodolfo Delgado-Lezama, Mariana Bravo-Hernández, Úrzula Franco-Enzástiga, Yarim E De la Luz-Cuellar, Nara S Alvarado-Cervantes, Guadalupe Raya-Tafolla, Luis A Martínez-Zaldivar, Alberto Vargas-Parada, Erick J Rodríguez-Palma, Guadalupe C Vidal-Cantú, Crystell G Guzmán-Priego, Jorge E Torres-López, Janet Murbartián, Ricardo Felix, Vinicio Granados-Soto

Affiliations

  1. Departamento de Fisiología, Biofísica y Neurociencias, Cinvestav, Mexico City, Mexico.
  2. Neuroregeneration Laboratory, Department of Anesthesiology, University of California, San Diego, La Jolla, CA, USA.
  3. Neurobiology of Pain Laboratory, Departamento de Farmacobiología, Cinvestav, Mexico City, Mexico.
  4. Mechanisms of Pain Laboratory, División Académica de Ciencias de la Salud, Universidad Juárez Autónoma de Tabasco, Villahermosa, Tabasco, Mexico.
  5. Hospital Regional de Alta Especialidad "Dr. Juan Graham Casasús", Villahermosa, Tabasco, Mexico.
  6. Departamento de Farmacobiología, Cinvestav, Mexico City, Mexico.
  7. Departamento de Biología Celular, Cinvestav, Mexico City, Mexico.

PMID: 34409771 PMCID: PMC8374381 DOI: 10.14814/phy2.14984

Abstract

Chronic pain is an incapacitating condition that affects a large population worldwide. Until now, there is no drug treatment to relieve it. The impairment of GABAergic inhibition mediated by GABA

© 2021 The Authors. Physiological Reports published by Wiley Periodicals LLC on behalf of The Physiological Society and the American Physiological Society.

Keywords: GABAA and GABAB receptors; Hoffmann reflex; Pain; extrasynaptic GABAA receptors

References

  1. Neuroreport. 2006 Aug 21;17(12):1331-5 - PubMed
  2. Front Cell Neurosci. 2017 Sep 19;11:283 - PubMed
  3. Nat Rev Drug Discov. 2011 Jul 29;10(9):685-97 - PubMed
  4. Eur J Pharmacol. 2019 Sep 5;858:172443 - PubMed
  5. J Physiol. 2011 Jun 1;589(Pt 11):2733-43 - PubMed
  6. Neurosci Lett. 2013 Dec 17;557 Pt A:43-51 - PubMed
  7. J Physiol. 1995 Jan 1;482 ( Pt 1):29-38 - PubMed
  8. Diagnostics (Basel). 2021 Feb 11;11(2): - PubMed
  9. J Comp Neurol. 1993 Dec 15;338(3):337-59 - PubMed
  10. Eur J Neurosci. 2000 Sep;12(9):3201-10 - PubMed
  11. Eur J Pain. 2017 Jul;21(6):1061-1071 - PubMed
  12. Nature. 2003 Aug 21;424(6951):938-42 - PubMed
  13. J Comp Neurol. 2012 Dec 1;520(17):3895-911 - PubMed
  14. J Neurosci. 2011 Jun 1;31(22):8134-42 - PubMed
  15. Prog Biophys Mol Biol. 2005 Jan;87(1):33-46 - PubMed
  16. Eur J Pain. 2003;7(4):345-51 - PubMed
  17. J Neurophysiol. 2018 Dec 1;120(6):2953-2974 - PubMed
  18. Life Sci. 1986 Nov 3;39(18):1667-74 - PubMed
  19. J Neurophysiol. 2013 Nov;110(9):2175-84 - PubMed
  20. Pain. 2011 Jun;152(6):1317-1326 - PubMed
  21. Neuropharmacology. 1996;35(9-10):1331-5 - PubMed
  22. J Physiol. 1996 Dec 15;497 ( Pt 3):753-9 - PubMed
  23. Pain. 2014 Feb;155(2):250-260 - PubMed
  24. Nature. 2005 Dec 15;438(7070):1017-21 - PubMed
  25. Pain. 2008 Nov 15;140(1):48-57 - PubMed
  26. Nat Rev Neurosci. 2010 Dec;11(12):823-36 - PubMed
  27. J Neurophysiol. 1998 Jan;79(1):181-9 - PubMed
  28. Pain. 2016 Mar;157(3):613-626 - PubMed
  29. J Neurosci. 1996 Jan;16(1):283-97 - PubMed
  30. Front Pharmacol. 2016 Nov 22;7:446 - PubMed
  31. Mol Pain. 2006 Nov 27;2:36 - PubMed
  32. J Physiol. 1998 Feb 1;506 ( Pt 3):795-808 - PubMed
  33. J Neurochem. 2021 Mar;156(6):897-916 - PubMed
  34. J Neurosci Res. 2017 Jun;95(6):1307-1318 - PubMed
  35. Adv Pharmacol. 2015;73:71-96 - PubMed
  36. Mol Cell Neurosci. 2003 Nov;24(3):818-30 - PubMed
  37. Pain. 2019 Jun;160(6):1448-1458 - PubMed
  38. Neurosci Lett. 2008 Jun 13;438(1):102-6 - PubMed
  39. Neuropharmacology. 2011 Jul-Aug;61(1-2):121-32 - PubMed
  40. J Neurosci. 1999 Jan 15;19(2):859-67 - PubMed
  41. Nat Commun. 2015 Apr 13;6:6803 - PubMed
  42. Nature. 2008 Jan 17;451(7176):330-4 - PubMed
  43. Neuron. 2001 Jul 19;31(1):47-58 - PubMed
  44. J Comp Neurol. 1996 Feb 12;365(3):392-412 - PubMed
  45. Exp Brain Res. 1999 Feb;124(4):395-421 - PubMed
  46. Annu Rev Pharmacol Toxicol. 2012;52:111-33 - PubMed
  47. J Neurosci. 2006 Feb 8;26(6):1833-43 - PubMed
  48. Eur J Pharmacol. 2014 Jul 5;734:91-7 - PubMed
  49. Nat Rev Neurosci. 2005 Mar;6(3):215-29 - PubMed
  50. Neuropharmacology. 2018 Jul 1;136(Pt A):102-105 - PubMed
  51. Science. 1965 Nov 19;150(3699):971-9 - PubMed
  52. Exp Brain Res. 1999 Nov;129(1):1-37 - PubMed
  53. Diabetes. 2017 May;66(5):1380-1390 - PubMed
  54. Biochem Biophys Res Commun. 2011 Aug 19;412(1):26-31 - PubMed

Publication Types