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Ann Otol Rhinol Laryngol. 2021 Sep 08;34894211045266. doi: 10.1177/00034894211045266. Epub 2021 Sep 08.

Pulmonary Function Tests May Better Predict Dyspnea-Severity in Patients with Subglottic Stenosis Compared to Clinician-Reported Stenosis.

The Annals of otology, rhinology, and laryngology

Neel K Bhatt, Valerie P Huang, Caitlin Bertelsen, William Z Gao, Lindsay S Reder, Michael M Johns, Karla O'Dell

Affiliations

  1. Department of Otolaryngology-Head and Neck Surgery, School of Medicine, University of Washington, St Louis, MO, USA.
  2. Tina and Rick Caruso Department of Otolaryngology-Head and Neck Surgery, University of Southern California, Los Angeles, CA, USA.
  3. Southern California Ear, Nose and Throat, Long Beach, CA, USA.
  4. Department of Otolaryngology-Head and Neck Surgery, Georgetown University Medical Center, Washington, DC, USA.
  5. Southern California Permanente Medical Group, Kaiser Permanente Baldwin Park, Baldwin Park, CA, USA.

PMID: 34496642 DOI: 10.1177/00034894211045266

Abstract

OBJECTIVE: Patients with subglottic stenosis (SGS) present with varied degree of breathing complaints. The dyspnea index (DI) is a 10-question patient-reported outcome measure designed to measure the severity of upper airway obstruction. We set out to determine whether pulmonary function tests or clinician-reported degree of stenosis best predicted DI scores.

METHODS: Thirty patients with SGS were retrospectively reviewed over a 6-year period. One visit from each patient was included. Data including peak expiratory flow rate (PEFR), body-mass index (BMI), clinician-reported degree of stenosis, and DI scores were reviewed. Multiple linear regression was performed to determine how degree of stenosis and PEFR % predicted the variation in DI score.

RESULTS: PEFR % better predicted DI scores compared to degree of stenosis (partial correlation -0.32 vs 0.17). After stepwise elimination, PEFR % remained in the regression and was significantly associated with DI scores (

CONCLUSION: This study suggests that pulmonary function tests may be a better in-office measure to substantiate the severity of symptoms in patients with SGS.

Keywords: dyspnea; pulmonary function tests; subglottic stenosis; upper airway obstruction

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