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Biolo G, Fiotti N, Cominotto F, et al. Ruling Out Coronavirus Disease 2019 in Patients with Pneumonia: The Role of Blood Cell Count and Lung Ultrasound. J Clin Med. 2021;10(16)doi: 10.3390/jcm10163481.
Biolo, G., Fiotti, N., Cominotto, F., Di Girolamo, F. G., Panizon, E., Altamura, N., Casarsa, C., Pipoli, A., Giordano, M., Torelli, L., Mearelli, F., & Vinci, P. (2021). Ruling Out Coronavirus Disease 2019 in Patients with Pneumonia: The Role of Blood Cell Count and Lung Ultrasound. Journal of clinical medicine, 10(16), . https://doi.org/10.3390/jcm10163481
Biolo, Gianni, et al. "Ruling Out Coronavirus Disease 2019 in Patients with Pneumonia: The Role of Blood Cell Count and Lung Ultrasound." Journal of clinical medicine vol. 10,16 (2021). doi: https://doi.org/10.3390/jcm10163481
Biolo G, Fiotti N, Cominotto F, Di Girolamo FG, Panizon E, Altamura N, Casarsa C, Pipoli A, Giordano M, Torelli L, Mearelli F, Vinci P. Ruling Out Coronavirus Disease 2019 in Patients with Pneumonia: The Role of Blood Cell Count and Lung Ultrasound. J Clin Med. 2021 Aug 06;10(16). doi: 10.3390/jcm10163481. PMID: 34441777; PMCID: PMC8397060.
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J Clin Med. 2021 Aug 06;10(16). doi: 10.3390/jcm10163481.

Ruling Out Coronavirus Disease 2019 in Patients with Pneumonia: The Role of Blood Cell Count and Lung Ultrasound.

Journal of clinical medicine

Gianni Biolo, Nicola Fiotti, Franco Cominotto, Filippo Giorgio Di Girolamo, Emiliano Panizon, Nicola Altamura, Chiara Casarsa, Alessandro Pipoli, Mauro Giordano, Lucio Torelli, Filippo Mearelli, Pierandrea Vinci

Affiliations

  1. Clinica Medica, Department of Medical Surgical and Health Sciences, University of Trieste, Strada di Fiume 447, 34149 Trieste, Italy.
  2. Emergency Department, ASUGI, Ospedale di Cattinara, Strada di Fiume 447, 34149 Trieste, Italy.
  3. Pharmacy Department, ASUGI, Ospedale di Cattinara, Strada di Fiume 447, 34149 Trieste, Italy.
  4. Department of Advanced Medical and Surgical Sciences, University of Campania, L. Vanvitelli, 80131 Naples, Italy.
  5. Biostatistics Unit, Department of Medical Surgical and Health Sciences, University of Trieste, Strada di Fiume 447, 34149 Trieste, Italy.

PMID: 34441777 PMCID: PMC8397060 DOI: 10.3390/jcm10163481

Abstract

Coronavirus disease 2019 (COVID-19) is characterized by a distinctive blood leucocyte pattern and B-lines on lung ultrasound (LUS) as marker of alveolar-interstitial syndrome. We aimed to evaluate the accuracy of blood leucocyte count alone or in combination with LUS for COVID-19 diagnosis. We retrospectively enrolled consecutive patients diagnosed with community acquired pneumonia (CAP) at hospital admission to derive and validate cutoff values for blood cell count that could be predictive of COVID-19 before confirmation by the nucleic acid amplification test (NAAT). Cutoff values, generated and confirmed in inception (41/115, positive/negative patients) and validation (100/180, positive/negative patients) cohorts, were ≤17 and ≤10 cells/mm

Keywords: COVID-19; basophils; community acquired pneumonia; eosinophils; lung ultrasound

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