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Gabryelska A, Chrzanowski J, Sochal M, et al. Nocturnal Oxygen Saturation Parameters as Independent Risk Factors for Type 2 Diabetes Mellitus among Obstructive Sleep Apnea Patients. J Clin Med. 2021;10(17)doi: 10.3390/jcm10173770.
Gabryelska, A., Chrzanowski, J., Sochal, M., Kaczmarski, P., Turkiewicz, S., Ditmer, M., Karuga, F. F., Czupryniak, L., & Białasiewicz, P. (2021). Nocturnal Oxygen Saturation Parameters as Independent Risk Factors for Type 2 Diabetes Mellitus among Obstructive Sleep Apnea Patients. Journal of clinical medicine, 10(17), . https://doi.org/10.3390/jcm10173770
Gabryelska, Agata, et al. "Nocturnal Oxygen Saturation Parameters as Independent Risk Factors for Type 2 Diabetes Mellitus among Obstructive Sleep Apnea Patients." Journal of clinical medicine vol. 10,17 (2021). doi: https://doi.org/10.3390/jcm10173770
Gabryelska A, Chrzanowski J, Sochal M, Kaczmarski P, Turkiewicz S, Ditmer M, Karuga FF, Czupryniak L, Białasiewicz P. Nocturnal Oxygen Saturation Parameters as Independent Risk Factors for Type 2 Diabetes Mellitus among Obstructive Sleep Apnea Patients. J Clin Med. 2021 Aug 24;10(17). doi: 10.3390/jcm10173770. PMID: 34501217; PMCID: PMC8432118.
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J Clin Med. 2021 Aug 24;10(17). doi: 10.3390/jcm10173770.

Nocturnal Oxygen Saturation Parameters as Independent Risk Factors for Type 2 Diabetes Mellitus among Obstructive Sleep Apnea Patients.

Journal of clinical medicine

Agata Gabryelska, Jędrzej Chrzanowski, Marcin Sochal, Piotr Kaczmarski, Szymon Turkiewicz, Marta Ditmer, Filip Franciszek Karuga, Leszek Czupryniak, Piotr Białasiewicz

Affiliations

  1. Department of Sleep Medicine and Metabolic Disorders, Medical University of Lodz, 92-215 Lodz, Poland.
  2. Department of Biostatistics and Translational Medicine, Medical University of Lodz, 92-215 Lodz, Poland.
  3. Department of Diabetology and Internal Medicine, Warsaw Medical University, 02-097 Warsaw, Poland.

PMID: 34501217 PMCID: PMC8432118 DOI: 10.3390/jcm10173770

Abstract

Obstructive sleep apnea (OSA) is a recognized independent risk factor for metabolic disorders, type 2 diabetes mellites (DM2) in particular. Therefore, the study aimed to assess the influence of nocturnal oxygen saturation parameters on the onset of DM2 among OSA patients. The study consisted of 549 participants, who underwent polysomnography examination. Based on apnea hypopnea index (AHI), 465 patients were diagnosed with OSA. One hundred and seven individuals had comorbid DM2. Cox regression models were used to assess the effect of oxygen saturation parameters on the onset of DM2. Classification and regression trees (CART) analysis was used to assess the onset of the DM2 in the study group in context of oxygen saturation variables. One-way Cox regression showed higher risk of earlier DM2 for increased values of BMI, AHI, decreased basal O

Keywords: O2 saturation; hypoxia; obstructive sleep apnea (OSA); polysomnography (PSG); risk factor; type 2 diabetes mellitus (DM2)

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