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Wakeman M. A Literature Review of the Potential Impact of Medication on Vitamin D Status. Risk Manag Healthc Policy. 2021;14:3357-3381doi: 10.2147/RMHP.S316897.
Wakeman, M. (2021). A Literature Review of the Potential Impact of Medication on Vitamin D Status. Risk management and healthcare policy, 143357-3381. https://doi.org/10.2147/RMHP.S316897
Wakeman, Michael. "A Literature Review of the Potential Impact of Medication on Vitamin D Status." Risk management and healthcare policy vol. 14 (2021): 3357-3381. doi: https://doi.org/10.2147/RMHP.S316897
Wakeman M. A Literature Review of the Potential Impact of Medication on Vitamin D Status. Risk Manag Healthc Policy. 2021 Aug 14;14:3357-3381. doi: 10.2147/RMHP.S316897. eCollection 2021. PMID: 34421316; PMCID: PMC8373308.
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Risk Manag Healthc Policy. 2021 Aug 14;14:3357-3381. doi: 10.2147/RMHP.S316897. eCollection 2021.

A Literature Review of the Potential Impact of Medication on Vitamin D Status.

Risk management and healthcare policy

Michael Wakeman

Affiliations

  1. Faculty of Health and Wellbeing, University of Sunderland, Sunderland, SR1 3SD, UK.

PMID: 34421316 PMCID: PMC8373308 DOI: 10.2147/RMHP.S316897

Abstract

In recent years, there has been a significant increase in media coverage of the putative actions of vitamin D as well as the possible health benefits that supplementation might deliver. However, the potential effect that medications may have on the vitamin D status is rarely taken into consideration. This literature review was undertaken to assess the degree to which vitamin D status may be affected by medication. Electronic databases were searched to identify literature relating to this subject, and study characteristics and conclusions were scrutinized for evidence of potential associations. The following groups of drugs were identified in one or more studies to affect vitamin D status in some way: anti-epileptics, laxatives, metformin, loop diuretics, angiotensin-converting enzyme inhibitors, thiazide diuretics, statins, calcium channel blockers, antagonists of vitamin K, platelet aggregation inhibitors, digoxin, potassium-sparing diuretics, benzodiazepines, antidepressants, proton pump inhibitors, histamine H

© 2021 Wakeman.

Keywords: cholecalciferol; drug interactions; ergocalciferol; medication interactions; vitamin D

Conflict of interest statement

The author reports no conflicts of interest in this work.

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