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Infect Drug Resist. 2021 Sep 02;14:3581-3588. doi: 10.2147/IDR.S324018. eCollection 2021.

Emergence of .

Infection and drug resistance

Sandip Patil, Hongyu Chen, Chunna Guo, Xiaoli Zhang, Pei-Gen Ren, Ngiambudulu M Francisco, Feiqiu Wen

Affiliations

  1. Shenzhen Institute of Advanced Technology, Shenzhen University Town, Shenzhen, Guangdong Province, People's Republic of China.
  2. Department of Haematology and Oncology, Shenzhen Children's Hospital, Shenzhen, Guangdong Province, People's Republic of China.
  3. Paediatric Research Institute, Shenzhen Children's Hospital, Shenzhen, Guangdong Province, People's Republic of China.
  4. Department of Laboratory Medicine, Shenzhen Children's Hospital, Shenzhen, Guangdong Province, People's Republic of China.
  5. Grupo de Investigação Microbiana e Imunológica, Instituto Nacional de Investigação em Saúde (National Institute for Health Research), Luanda, Angola.

PMID: 34511949 PMCID: PMC8422287 DOI: 10.2147/IDR.S324018

Abstract

AIM: We investigated the clonal diversity of carbapenemase-producing

METHODS: From January 2014 to December 2018, a total number of 36 unique carbapenemase-producing clinical isolates of

RESULTS: The isolates showed resistance to ceftazidime, ertapenem, ampicillin, cefazolin, ceftriaxone, cefotetan, ticarcillin, cefaclor, cefpodoxime, azlocillin, cefcapene, mezlocillin and ampicillin-sulbactam. Of the 36

CONCLUSION: This study reports on the occurrence and spread of carbapenemase and extended-spectrum β-lactamase encoding genes co-existence in sporadic

© 2021 Patil et al.

Keywords: ESBLs; Klebsiella pneumoniae; antimicrobial susceptibility; carbapenemase; molecular characterization

Conflict of interest statement

The authors report no conflicts of interest in this work.

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