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Viruses. 2021 Jul 22;13(8). doi: 10.3390/v13081423.

Lack of Association between Adverse Pregnancy Outcomes and Zika Antibodies among Pregnant Women in Thailand between 1997 and 2015.

Viruses

Nicole Ngo-Giang-Huong, Charline Leroi, Dahlene Fusco, Tim R Cressey, Nantawan Wangsaeng, Nicolas Salvadori, Natedao Kongyai, Wasna Sirirungsi, Marc Lallemant, Prasert Auewarakul, Woottichai Khamduang, Gonzague Jourdain

Affiliations

  1. Maladies Infectieuses et Vecteurs: Écologie, Génétique, Évolution et Contrôle (MIVEGEC), Agropolis University Montpellier, Centre National de la Recherche Scientifique (CNRS), Institut de Recherche Pour le Développement (IRD), 34394 Montpellier, France.
  2. Associated Medical Sciences (AMS)-PHPT Research Collaboration, Chiang Mai 50200, Thailand.
  3. Department of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai University, 110 Inthawaroros Road, Sripoom, Muang, Chiang Mai 50200, Thailand.
  4. Department of Medicine, Tulane University, 1430 Tulane Avenue, New Orleans, LA 70112, USA.
  5. Department of Microbiology, Faculty of Medicine Siriraj Hospital, Mahidol University, 2 Wanglang Road, Bangkoknoi, Bangkok 10700, Thailand.

PMID: 34452289 PMCID: PMC8402824 DOI: 10.3390/v13081423

Abstract

Data about Zika virus infection and adverse pregnancy outcomes in Southeast Asia are scarce. We conducted an unmatched case-control study of Zika virus (ZIKV) serology in pregnant women enrolled in human immunodeficiency virus (HIV) or hepatitis B virus (HBV) perinatal prevention trials between 1997 and 2015 in Thailand. Case and control groups included women with and without adverse pregnancy outcomes. Plasma samples collected during the last trimester of pregnancy were tested for ZIKV IgG/IgM and Dengue IgG/IgM (Euroimmun, AG, Germany). Case newborn plasma samples were tested for ZIKV IgM and ZIKV RNA (Viasure, Spain). The case group included women with stillbirth (

Keywords: Thailand; Zika virus; Zika virus serology; adverse pregnancy outcomes; dengue virus serology; neonates; pregnant women

References

  1. N Engl J Med. 2000 Oct 5;343(14):982-91 - PubMed
  2. AIDS. 2015 Nov 28;29(18):2497-507 - PubMed
  3. Emerg Infect Dis. 2019 Dec;25(12):2264-2265 - PubMed
  4. N Engl J Med. 2016 Dec 15;375(24):2321-2334 - PubMed
  5. Int J Infect Dis. 2020 Apr;93:151-159 - PubMed
  6. Emerg Infect Dis. 2018 Sep;24(9): - PubMed
  7. Clin Infect Dis. 2010 Mar 15;50(6):898-908 - PubMed
  8. J Clin Microbiol. 2017 Jul;55(7):2127-2136 - PubMed
  9. N Engl J Med. 2004 Jul 15;351(3):217-28 - PubMed
  10. Lancet Infect Dis. 2019 Apr;19(4):439-446 - PubMed
  11. Sci Rep. 2018 Nov 21;8(1):17193 - PubMed
  12. Trans R Soc Trop Med Hyg. 1963 Sep;57:364-71 - PubMed
  13. PLoS Pathog. 2020 Dec 31;16(12):e1009068 - PubMed
  14. Lancet Infect Dis. 2020 Dec;20(12):1446-1456 - PubMed
  15. Microbiol Resour Announc. 2018 Sep 20;7(11): - PubMed
  16. Virol J. 2018 Jul 13;15(1):108 - PubMed
  17. Nature. 2016 Aug 4;536(7614):48-53 - PubMed
  18. J Infect Public Health. 2020 Jan;13(1):11-15 - PubMed
  19. Int J Infect Dis. 2020 Dec;101:90-97 - PubMed
  20. Nat Immunol. 2016 Sep;17(9):1102-8 - PubMed
  21. N Engl J Med. 2018 Mar 08;378(10):911-923 - PubMed
  22. Genome Announc. 2018 Mar 8;6(10): - PubMed
  23. Viral Immunol. 2020 Jan/Feb;33(1):3-11 - PubMed
  24. Am J Trop Med Hyg. 2015 Aug;93(2):380-383 - PubMed
  25. J Med Assoc Thai. 2016 Feb;99(2):175-81 - PubMed
  26. Euro Surveill. 2016 Apr 21;21(16): - PubMed
  27. Int J Gynaecol Obstet. 2018 Dec;143(3):277-281 - PubMed
  28. J Clin Microbiol. 2017 Aug;55(8):2462-2471 - PubMed
  29. Am J Trop Med Hyg. 2018 Sep;99(3):780-782 - PubMed

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