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Shchelkunov SN, Sergeev AA, Yakubitskiy SN, et al. Adaptive Immune Response to Vaccinia Virus LIVP Infection of BALB/c Mice and Protection against Lethal Reinfection with Cowpox Virus. Viruses. 2021;13(8)doi: 10.3390/v13081631.
Shchelkunov, S. N., Sergeev, A. A., Yakubitskiy, S. N., Titova, K. A., Pyankov, S. A., Kolosova, I. V., Starostina, E. V., Borgoyakova, M. B., Zadorozhny, A. M., Kisakov, D. N., Shulgina, I. S., & Karpenko, L. I. (2021). Adaptive Immune Response to Vaccinia Virus LIVP Infection of BALB/c Mice and Protection against Lethal Reinfection with Cowpox Virus. Viruses, 13(8), . https://doi.org/10.3390/v13081631
Shchelkunov, Sergei N, et al. "Adaptive Immune Response to Vaccinia Virus LIVP Infection of BALB/c Mice and Protection against Lethal Reinfection with Cowpox Virus." Viruses vol. 13,8 (2021). doi: https://doi.org/10.3390/v13081631
Shchelkunov SN, Sergeev AA, Yakubitskiy SN, Titova KA, Pyankov SA, Kolosova IV, Starostina EV, Borgoyakova MB, Zadorozhny AM, Kisakov DN, Shulgina IS, Karpenko LI. Adaptive Immune Response to Vaccinia Virus LIVP Infection of BALB/c Mice and Protection against Lethal Reinfection with Cowpox Virus. Viruses. 2021 Aug 17;13(8). doi: 10.3390/v13081631. PMID: 34452494; PMCID: PMC8402668.
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Viruses. 2021 Aug 17;13(8). doi: 10.3390/v13081631.

Adaptive Immune Response to Vaccinia Virus LIVP Infection of BALB/c Mice and Protection against Lethal Reinfection with Cowpox Virus.

Viruses

Sergei N Shchelkunov, Alexander A Sergeev, Stanislav N Yakubitskiy, Ksenia A Titova, Stepan A Pyankov, Irina V Kolosova, Ekaterina V Starostina, Mariya B Borgoyakova, Alexey M Zadorozhny, Denis N Kisakov, Irina S Shulgina, Larisa I Karpenko

Affiliations

  1. State Research Center of Virology and Biotechnology VECTOR, Rospotrebnadzor, 630559 Koltsovo, Russia.

PMID: 34452494 PMCID: PMC8402668 DOI: 10.3390/v13081631

Abstract

Mass vaccination has played a critical role in the global eradication of smallpox. Various vaccinia virus (VACV) strains, whose origin has not been clearly documented in most cases, have been used as live vaccines in different countries. These VACV strains differed in pathogenicity towards various laboratory animals and in reactogenicity exhibited upon vaccination of humans. In this work, we studied the development of humoral and cellular immune responses in BALB/c mice inoculated intranasally (i.n.) or intradermally (i.d.) with the VACV LIVP strain at a dose of 10

Keywords: T cells; adaptive immune response; antibodies; poxviruses; protection; vaccines; vaccinia virus

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