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Ali Q, Bilal MI, Ansari FA, et al. Neuroblastoma: A Case of Massive Hepatomegaly. Cureus. 2021;13(7):e16731doi: 10.7759/cureus.16731.
Ali, Q., Bilal, M. I., Ansari, F. A., Gondal, M. U. R., & Arif, A. (2021). Neuroblastoma: A Case of Massive Hepatomegaly. Cureus, 13(7), e16731. https://doi.org/10.7759/cureus.16731
Ali, Qamar, et al. "Neuroblastoma: A Case of Massive Hepatomegaly." Cureus vol. 13,7 (2021): e16731. doi: https://doi.org/10.7759/cureus.16731
Ali Q, Bilal MI, Ansari FA, Gondal MUR, Arif A. Neuroblastoma: A Case of Massive Hepatomegaly. Cureus. 2021 Jul 29;13(7):e16731. doi: 10.7759/cureus.16731. eCollection 2021 Jul. PMID: 34513362; PMCID: PMC8412194.
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Cureus. 2021 Jul 29;13(7):e16731. doi: 10.7759/cureus.16731. eCollection 2021 Jul.

Neuroblastoma: A Case of Massive Hepatomegaly.

Cureus

Qamar Ali, Muhammad Ibraiz Bilal, Fawwad A Ansari, Muhammad Umer Riaz Gondal, Adnan Arif

Affiliations

  1. Paediatrics, Shifa International Hospital Islamabad, Islamabad, PAK.
  2. Internal Medicine, Shifa International Hospital Islamabad, Islamabad, PAK.
  3. Diagnostic Radiology, Shifa International Hospital Islamabad, Islamabad, PAK.

PMID: 34513362 PMCID: PMC8412194 DOI: 10.7759/cureus.16731

Abstract

Neuroblastoma is the most common embryonal tumor of childhood and has a variable presentation. Stage 4S neuroblastoma, described as a localized primary tumor in an infant with metastasis to skin, liver, or bone marrow, is an exception to the poor prognosis seen in widespread metastasis of neuroblastoma. Survival in infants with this stage of the disease is over 90%. Stage 4S with massive liver involvement, however, confers a poor prognosis. We need more research on the optimum treatment modality for patients with Stage 4S disease and massive hepatomegaly to improve patient outcomes.

Copyright © 2021, Ali et al.

Keywords: chemotherapy; hepatomegaly; management; neuroblastoma; prognosis

Conflict of interest statement

The authors have declared that no competing interests exist.

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