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Vanuytsel T, Tack J, Farre R. The Role of Intestinal Permeability in Gastrointestinal Disorders and Current Methods of Evaluation. Front Nutr. 2021;8:717925doi: 10.3389/fnut.2021.717925.
Vanuytsel, T., Tack, J., & Farre, R. (2021). The Role of Intestinal Permeability in Gastrointestinal Disorders and Current Methods of Evaluation. Frontiers in nutrition, 8717925. https://doi.org/10.3389/fnut.2021.717925
Vanuytsel, Tim, et al. "The Role of Intestinal Permeability in Gastrointestinal Disorders and Current Methods of Evaluation." Frontiers in nutrition vol. 8 (2021): 717925. doi: https://doi.org/10.3389/fnut.2021.717925
Vanuytsel T, Tack J, Farre R. The Role of Intestinal Permeability in Gastrointestinal Disorders and Current Methods of Evaluation. Front Nutr. 2021 Aug 26;8:717925. doi: 10.3389/fnut.2021.717925. eCollection 2021. PMID: 34513903; PMCID: PMC8427160.
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Front Nutr. 2021 Aug 26;8:717925. doi: 10.3389/fnut.2021.717925. eCollection 2021.

The Role of Intestinal Permeability in Gastrointestinal Disorders and Current Methods of Evaluation.

Frontiers in nutrition

Tim Vanuytsel, Jan Tack, Ricard Farre

Affiliations

  1. Department of Chronic Diseases, Translational Research Center for Gastrointestinal Disorders, Metabolism and Ageing, Catholic University Leuven, Leuven, Belgium.
  2. Division of Gastroenterology and Hepatology, Leuven University Hospital, Leuven, Belgium.

PMID: 34513903 PMCID: PMC8427160 DOI: 10.3389/fnut.2021.717925

Abstract

An increased intestinal permeability has been described in various gastrointestinal and non-gastrointestinal disorders. Nevertheless, the concept and definition of intestinal permeability is relatively broad and includes not only an altered paracellular route, regulated by tight junction proteins, but also the transcellular route involving membrane transporters and channels, and endocytic mechanisms. Paracellular intestinal permeability can be assessed

Copyright © 2021 Vanuytsel, Tack and Farre.

Keywords: GI diseases; bile acid malabsorption; chronic liver disease; coeliac disease; inflammatory bowel disease; intestinal permeability; paracellular route; transcellular route

Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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