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Cepas-Guillen PL, de la Fuente Mancera JC, Guzman Bofarull J, et al. Initial Results after the Implementation of an Edge-To-Edge Transcatheter Tricuspid Valve Repair Program. J Clin Med. 2021;10(18)doi: 10.3390/jcm10184252.
Cepas-Guillen, P. L., de la Fuente Mancera, J. C., Guzman Bofarull, J., Farrero, M., Regueiro, A., Brugaletta, S., Ibañez, C., Sanchis, L., Sitges, M., Sabate, M., & Freixa, X. (2021). Initial Results after the Implementation of an Edge-To-Edge Transcatheter Tricuspid Valve Repair Program. Journal of clinical medicine, 10(18), . https://doi.org/10.3390/jcm10184252
Cepas-Guillen, Pedro Luis, et al. "Initial Results after the Implementation of an Edge-To-Edge Transcatheter Tricuspid Valve Repair Program." Journal of clinical medicine vol. 10,18 (2021). doi: https://doi.org/10.3390/jcm10184252
Cepas-Guillen PL, de la Fuente Mancera JC, Guzman Bofarull J, Farrero M, Regueiro A, Brugaletta S, Ibañez C, Sanchis L, Sitges M, Sabate M, Freixa X. Initial Results after the Implementation of an Edge-To-Edge Transcatheter Tricuspid Valve Repair Program. J Clin Med. 2021 Sep 19;10(18). doi: 10.3390/jcm10184252. PMID: 34575362; PMCID: PMC8471561.
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J Clin Med. 2021 Sep 19;10(18). doi: 10.3390/jcm10184252.

Initial Results after the Implementation of an Edge-To-Edge Transcatheter Tricuspid Valve Repair Program.

Journal of clinical medicine

Pedro Luis Cepas-Guillen, Juan Carlos de la Fuente Mancera, Joan Guzman Bofarull, Marta Farrero, Ander Regueiro, Salvatore Brugaletta, Cristina Ibañez, Laura Sanchis, Marta Sitges, Manel Sabate, Xavier Freixa

Affiliations

  1. Cardiology Department, Cardiovascular Institute (ICCV), Hospital Clinic, IDIBAPS, University of Barcelona, 08036 Barcelona, Spain.
  2. Anesthesiology Department, Hospital Clinic, IDIBAPS, University of Barcelona, 08036 Barcelona, Spain.

PMID: 34575362 PMCID: PMC8471561 DOI: 10.3390/jcm10184252

Abstract

Transcatheter tricuspid valve repair (TTVr) has emerged as an alternative for the treatment of severe tricuspid regurgitation (TR). We report our initial experience with an edge-to-edge TTVr system in a high-volume institution.

METHODS: We included consecutive patients who underwent edge-to-edge TTVr systems. The primary efficacy endpoint was a reduction in the TR of at least one grade. The primary safety endpoint was procedure-related clinical serious adverse events.

RESULTS: A total of 28 patients underwent TTVr with edge-to-edge systems. All patients presented with at least severe TR with a high impact on quality of life (82% of patients in NYHA class ≥ III). The Triclip system was the most used device (89%). The primary efficacy endpoint was met in all patients. Only one patient experienced a procedural complication (femoral pseudoaneurysm). At three-month follow-up, 83% of patients were in NYHA I or II (18% baseline vs. 83% 3 months follow-up;

CONCLUSIONS: Edge-to-edge TTVr systems seem to represent a very valid alternative to prevent morbidity and mortality associated with TR as depicted by the favorable efficacy and safety.

Keywords: heart failure; transcatheter valve repair; tricuspid regurgitation

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