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Renn A, Adejolu M, Messiou C, et al. Overview of malignant soft-tissue sarcomas of the limbs. Clin Radiol. 2021;76(12):940.e1-940.e16doi: 10.1016/j.crad.2021.08.011.
Renn, A., Adejolu, M., Messiou, C., Bhaludin, B., Strauss, D. C., Thway, K., & Moskovic, E. (2021). Overview of malignant soft-tissue sarcomas of the limbs. Clinical radiology, 76(12), 940.e1-940.e16. https://doi.org/10.1016/j.crad.2021.08.011
Renn, A, et al. "Overview of malignant soft-tissue sarcomas of the limbs." Clinical radiology vol. 76,12 (2021): 940.e1-940.e16. doi: https://doi.org/10.1016/j.crad.2021.08.011
Renn A, Adejolu M, Messiou C, Bhaludin B, Strauss DC, Thway K, Moskovic E. Overview of malignant soft-tissue sarcomas of the limbs. Clin Radiol. 2021 Dec;76(12):940.e1-940.e16. doi: 10.1016/j.crad.2021.08.011. Epub 2021 Oct 01. PMID: 34607656.
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Clin Radiol. 2021 Dec;76(12):940.e1-940.e16. doi: 10.1016/j.crad.2021.08.011. Epub 2021 Oct 01.

Overview of malignant soft-tissue sarcomas of the limbs.

Clinical radiology

A Renn, M Adejolu, C Messiou, B Bhaludin, D C Strauss, K Thway, E Moskovic

Affiliations

  1. The Royal Marsden Hospital, 203 Fulham Rd, Chelsea, London, SW3 6JJ, UK. Electronic address: [email protected].
  2. The Royal Marsden Hospital, 203 Fulham Rd, Chelsea, London, SW3 6JJ, UK.

PMID: 34607656 DOI: 10.1016/j.crad.2021.08.011

Abstract

Although soft-tissue masses are common, sarcomas are rare malignant neoplasms showing variable mesenchymal differentiation and can occur at any anatomical site. Limb soft-tissue sarcomas (STS) are rare, but often lethal tumours. Although there are scores of historical pathological subtypes, this article will deal with the commonest: liposarcoma, leiomyosarcoma (LMS), undifferentiated pleomorphic sarcoma (UPS), synovial sarcoma, myxofibrosarcoma, malignant peripheral nerve sheath tumour (MPNST), epithelioid sarcoma, alveolar rhabdosarcoma, angiosarcoma and radiation-induced sarcoma (RIS). Following a review of >4,000 adult patients with limb sarcoma from our specialist soft-tissue tumour database, we summarise the literature and their imaging findings, with emphasis on radiological hallmarks that can aide in diagnosis and management. Increased awareness of sarcoma when challenged with a new mass in the extremity can ensure timely and appropriate treatment.

Copyright © 2021 The Royal College of Radiologists. Published by Elsevier Ltd. All rights reserved.

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