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J Cell Biochem. 2021 Dec;122(12):1903-1914. doi: 10.1002/jcb.30150. Epub 2021 Sep 22.

Cytotoxic effect of carbohydrate derivatives of digitoxigenin involves modulation of plasma membrane Ca.

Journal of cellular biochemistry

Jéssica Martins de Moura Valadares, Sumit O Bajaj, Hongyan Li, Hua-Yu L Wang, Simone Cavalcante Silva, Israel José Pereira Garcia, Duane Gischewiski Pereira, Pedro Azalim, Luis Eduardo Menezes Quintas, François Noël, Vanessa Faria Cortes, George Augustine O'Doherty, Leandro Augusto Barbosa

Affiliations

  1. Campus Centro-Oeste Dona Lindú, Laboratório de Bioquímica Celular, Universidade Federal de São João Del-Rei, Divinópolis, Minas Gerais, Brazil.
  2. Department of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts, USA.
  3. Instituto de Ciências Biomédicas, Laboratório de Farmacologia Bioquímica e Molecular, Universidade Federal do Rio de Janeiro, Rio de Janeiro, State of Rio de Janeiro, Brazil.

PMID: 34553411 DOI: 10.1002/jcb.30150

Abstract

Cardiac glycosides, such as digoxin and digitoxin, are compounds that interact with Na

© 2021 Wiley Periodicals LLC.

Keywords: HeLa cells; P-type ATPases; cardiac glycosides; digitoxin; digoxin; sodium-potassium-exchanging ATPase

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