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J Ophthalmic Inflamm Infect. 2021 Nov 01;11(1):31. doi: 10.1186/s12348-021-00263-1.

Acute posterior multifocal placoid pigment epitheliopathy (APMPPE).

Journal of ophthalmic inflammation and infection

Ilaria Testi, Sandra Vermeirsch, Carlos Pavesio

Affiliations

  1. Department of Uveitis, Moorfields Eye Hospital, National Health Service Foundation Trust, 162 City Rd, Old Street, London, EC1V 2PD, UK.
  2. Department of Uveitis, Moorfields Eye Hospital, National Health Service Foundation Trust, 162 City Rd, Old Street, London, EC1V 2PD, UK. [email protected].

PMID: 34524577 PMCID: PMC8443720 DOI: 10.1186/s12348-021-00263-1

Abstract

BACKGROUND: Acute posterior multifocal placoid pigment epitheliopathy (APMPPE) is a rare inflammatory eye disease, affecting the inner choroid and the outer retina. Recent advances in multimodal imaging have been important in the understanding of the pathophysiology of the disease, allowing a better characterization of the morphology of this condition.

METHODS: Narrative review.

RESULTS: In this review, a comprehensive overview of clinical features, imaging findings, treatment management, and long-term outcomes of patients with APMPPE will be provided.

CONCLUSIONS: Although APMPPE was originally believed to be a self-limited condition with a good prognosis, the disease can be recurrent and result in significant loss of vision function. Fundus imaging plays an important role in the diagnosis and management of the disease, allowing to evaluate response to treatment and onset of complications.

© 2021. The Author(s).

Keywords: APMPPE; Acute posterior multifocal placoid pigment epitheliopathy; Imaging; Optical coherence tomography angiography; Placoid epiteliopathy

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