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Han ZH, He ZM, Chen WH, et al. Octreotide-induced acute life-threatening gallstones after vicarious contrast medium excretion: A case report. World J Clin Cases. 2021;9(25):7484-7489doi: 10.12998/wjcc.v9.i25.7484.
Han, Z. H., He, Z. M., Chen, W. H., Wang, C. Y., & Wang, Q. (2021). Octreotide-induced acute life-threatening gallstones after vicarious contrast medium excretion: A case report. World journal of clinical cases, 9(25), 7484-7489. https://doi.org/10.12998/wjcc.v9.i25.7484
Han, Zong-Hong, et al. "Octreotide-induced acute life-threatening gallstones after vicarious contrast medium excretion: A case report." World journal of clinical cases vol. 9,25 (2021): 7484-7489. doi: https://doi.org/10.12998/wjcc.v9.i25.7484
Han ZH, He ZM, Chen WH, Wang CY, Wang Q. Octreotide-induced acute life-threatening gallstones after vicarious contrast medium excretion: A case report. World J Clin Cases. 2021 Sep 06;9(25):7484-7489. doi: 10.12998/wjcc.v9.i25.7484. PMID: 34616816; PMCID: PMC8464451.
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World J Clin Cases. 2021 Sep 06;9(25):7484-7489. doi: 10.12998/wjcc.v9.i25.7484.

Octreotide-induced acute life-threatening gallstones after vicarious contrast medium excretion: A case report.

World journal of clinical cases

Zong-Hong Han, Zhong-Ming He, Wen-Hua Chen, Cao-Ye Wang, Qi Wang

Affiliations

  1. Department of Interventional Radiology, The First People's Hospital of Changzhou, Changzhou 213003, Jiangsu Province, China.
  2. Department of Interventional Radiology, The First People's Hospital of Changzhou, Changzhou 213003, Jiangsu Province, China. [email protected].

PMID: 34616816 PMCID: PMC8464451 DOI: 10.12998/wjcc.v9.i25.7484

Abstract

BACKGROUND: Octreotide is widely used for the treatment of acromegaly, neuroendocrine tumors, and secretory diarrhea. However, long-term octreotide treatment can increase the incidence of gallstones. Vicarious contrast medium excretion (VCME) through the hepatobiliary system is well known. However, few studies have reported octreotide-induced acute gallstones following VCME.

CASE SUMMARY: A 69-year-old man presented with left lower back pain and hematuria caused by a fall. The patient had a history of polycystic kidney disease. VCME occurred following renal artery embolization for a ruptured polycystic kidney. After 5 d of treatment with octreotide, the patient developed acute gallstones and intrahepatic cholestasis which further induced pancreatitis and cholangitis. He was discharged after hemodialysis, antibiotics, and supportive treatments.

CONCLUSION: For patients with a high-risk of VCME, octreotide should be cautiously administered and carefully monitored.

©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.

Keywords: Case report; Contrast medium; Gallstones; Octreotide

Conflict of interest statement

Conflict-of-interest statement: The authors declare that they have no conflict of interest.

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