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Talluri S, Goedde MA, Coventry S, et al. Case Report: Rare Presentation of Mixed Germ Cell Tumor in an Infant. Front Pediatr. 2021;9:729917doi: 10.3389/fped.2021.729917.
Talluri, S., Goedde, M. A., Coventry, S., Rosenberg, E., Canalichio, K. L., Peppas, D., & White, J. T. (2021). Case Report: Rare Presentation of Mixed Germ Cell Tumor in an Infant. Frontiers in pediatrics, 9729917. https://doi.org/10.3389/fped.2021.729917
Talluri, Sriharsha, et al. "Case Report: Rare Presentation of Mixed Germ Cell Tumor in an Infant." Frontiers in pediatrics vol. 9 (2021): 729917. doi: https://doi.org/10.3389/fped.2021.729917
Talluri S, Goedde MA, Coventry S, Rosenberg E, Canalichio KL, Peppas D, White JT. Case Report: Rare Presentation of Mixed Germ Cell Tumor in an Infant. Front Pediatr. 2021 Sep 07;9:729917. doi: 10.3389/fped.2021.729917. eCollection 2021. PMID: 34557461; PMCID: PMC8453063.
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Front Pediatr. 2021 Sep 07;9:729917. doi: 10.3389/fped.2021.729917. eCollection 2021.

Case Report: Rare Presentation of Mixed Germ Cell Tumor in an Infant.

Frontiers in pediatrics

Sriharsha Talluri, Michael A Goedde, Susan Coventry, Eran Rosenberg, Katie L Canalichio, Dennis Peppas, Jeffrey T White

Affiliations

  1. Department of Urology, University of Louisville, Louisville, KY, United States.
  2. Department of Pediatric Anatomic Pathology, Norton Healthcare, Louisville, KY, United States.
  3. Department of Pediatric Urology, Norton Healthcare, Louisville, KY, United States.

PMID: 34557461 PMCID: PMC8453063 DOI: 10.3389/fped.2021.729917

Abstract

The estimated incidence of pediatric testis tumor is 0.5-2.0 per 100,000 children, accounting for 1-2% of all pediatric tumors. Mixed germ cell tumors (MGCT) in prepubertal males are exceedingly rare, with only one previous case report found in the literature. We report a case of a MGCT in an infant. For prepubertal males, GCTs typically present with a painless scrotal mass, though trauma, testis torsion and hydrocele are also common presentations. Similar to such tumors in postpubertal males, ultrasonography, computed tomography, and tumor markers are integral to determine the best treatment. The patient described in this report presented with a painless scrotal mass. Following orchiectomy, the patient was found to have MGCT that was limited to the testis. With prudent management, these patients tend to have favorable prognoses.

Copyright © 2021 Talluri, Goedde, Coventry, Rosenberg, Canalichio, Peppas and White.

Keywords: germ cell tumor; pediatric cancer; pediatric urology; surgery; testicular tumor

Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

References

  1. J Clin Oncol. 2004 Sep 1;22(17):3563-9 - PubMed
  2. Urology. 2012 Apr;79(4):892-7 - PubMed
  3. J Pediatr Surg. 2003 Mar;38(3):319-24; discussion 319-24 - PubMed
  4. Eur Urol. 2016 Jul;70(1):93-105 - PubMed
  5. Hum Pathol. 1997 Apr;28(4):404-10 - PubMed
  6. Acta Oncol. 1992;31(7):749-53 - PubMed
  7. Urol Oncol. 2016 Feb;34(2):65-75 - PubMed
  8. Insights Imaging. 2020 May 27;11(1):74 - PubMed
  9. J Clin Oncol. 2013 Oct 1;31(28):3490-3 - PubMed
  10. Cancer. 2010 Oct 15;116(20):4882-91 - PubMed
  11. Am J Surg Pathol. 1994 Sep;18(9):947-52 - PubMed
  12. Cancer. 1989 Aug 1;64(3):715-20 - PubMed
  13. Hum Pathol. 2017 Jan;59:10-25 - PubMed
  14. J Urol. 2003 Dec;170(6 Pt 1):2412-5; discussion 2415-6 - PubMed
  15. Rev Urol. 2004 Winter;6(1):11-8 - PubMed
  16. J Indian Assoc Pediatr Surg. 2019 Apr-Jun;24(2):144-146 - PubMed
  17. J Urol. 1991 Nov;146(5):1295-8 - PubMed
  18. J Urol. 1995 Jan;153(1):85-9 - PubMed
  19. J Urol. 1993 Feb;149(2):353-6 - PubMed
  20. J Pediatr Urol. 2018 Oct;14(5):443.e1-443.e7 - PubMed
  21. J Clin Oncol. 2004 Jul 1;22(13):2691-700 - PubMed
  22. Med Pediatr Oncol. 1994;22(5):329-40 - PubMed

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